Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/9775
Title
Spread of different rhinovirus B genotypes in hospitalized children in Spain
Author(s)
Cuevas, Maria Teresa ISCIII | Molinero, Mar ISCIII | Pozo Sanchez, Francisco ISCIII | Calvo, Cristina | García-García, María Luz | Reyes, Noelia ISCIII | Ledesma, Juan ISCIII | Casas Flecha, Inmaculada ISCIII
Date issued
2013-09
Citation
Influenza Other Respir Viruses. 2013 Sep;7(5):623-8.
Language
Inglés
Abstract
Human Rhinovirus (HRV) classification is an evolving process. New genotypes have been described within HRV-A and HRV-C species, but only one has been accepted related to HRV-B. From 2003 to 2010, a total of 3987 nasopharyngeal aspirate samples were taken from pediatric patients admitted to the Severo Ochoa Hospital in Madrid (Spain). After viral analysis, 949 (23.8%) tested positive to HRV. A random selection of 397 (42%) positive samples showed that 39 (9.8%) were HRV-B. The sequencing of partial VP4/VP2 coding region revealed the spread of 13 of 25 defined HRV-B serotypes and three putative new genotypes. Such results remark the high diversity of HRV-B.
Subject
MESH
Adolescent | Child | Child, Hospitalized | Child, Preschool | Female | Genotype | Humans | Infant | Male | Molecular Sequence Data | Phylogeny | Picornaviridae Infections | Respiratory Tract Infections | Rhinovirus | Spain
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