Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/9619
Title
Clec2d Joins the Cell Death Sensor Ranks
Author(s)
del Fresno, Carlos CNIC | Sancho, David CNIC
Date issued
2020-01
Citation
Immunity. 2020; 52(1):6-8
Language
Inglés
Abstract
Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity. In this issue of Immunity, Lai et al. (2020) uncover a role for the C-type lectin receptor Clec2d as a sensor of cell death, which directly detects histones released during necrosis and thus contributes to inflammation and immunopathology.
MESH
Cell Death | Humans | Inflammation | Necrosis | Receptors, Cell Surface | Histones | Lectins, C-Type
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DOI
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