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dc.contributor.authorMonsalve Arteaga, Lía
dc.contributor.authorMuñoz Bellido, Juan Luis
dc.contributor.authorVieira Lista, María Carmen
dc.contributor.authorVicente Santiago, María Belén
dc.contributor.authorFernández Soto, Pedro
dc.contributor.authorBas, Isabel 
dc.contributor.authorLeralta, Nuria 
dc.contributor.authorDe Ory, Fernando de 
dc.contributor.authorNegredo, Anabel 
dc.contributor.authorSánchez-Seco, María Paz 
dc.contributor.authorAlonso Sardón, Montserrat
dc.contributor.authorPérez González, Sonia
dc.contributor.authorJiménez Del Bianco, Ana
dc.contributor.authorBlanco Peris, Lydia
dc.contributor.authorAlamo-Sanz, Rufino
dc.contributor.authorHewson, Roger
dc.contributor.authorBelhassen-García, Moncef
dc.contributor.authorMuro, Antonio
dc.date.accessioned2020-04-15T08:01:13Z
dc.date.available2020-04-15T08:01:13Z
dc.date.issued2020-03
dc.identifier.citationEuro Surveill. 2020 Mar;25(10).es_ES
dc.identifier.issn1560-7917es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/9562
dc.description.abstractBackgroundCrimean-Congo haemorrhagic fever virus (CCHFV) is considered an emerging or even a probable re-emerging pathogen in southern Europe. Presence of this virus had been reported previously in Spain in 2010.AimWe aimed to evaluate the potential circulation of CCHFV in western Spain with a serosurvey in asymptomatic adults (blood donors).MethodsDuring 2017 and 2018, we conducted a CCHFV serosurvey in randomly selected asymptomatic blood donors from western Spain. Three assays using specific IgG antibodies against CCHFV were performed: the VectoCrimea ELISA test, an in-house ELISA and indirect immunofluorescence (EuroImmun) test with glycoprotein and nucleoprotein.ResultsA total of 516 blood donors participated in this cross-sectional study. The majority of the study participants were male (68.4%), and the mean age was 46.3 years. Most of the participants came from rural areas (86.8%) and 68.6% had contact with animals and 20.9% had animal husbandry practices. One in five participants (109/516, 21.1%) were engaged in at-risk professional activities such as agriculture and shepherding, slaughtering, hunting, veterinary and healthcare work (mainly nursing staff and laboratory technicians). A total of 15.3% of the participants were bitten by ticks in the days or months before the date of sampling. We detected anti-CCHFV IgG antibodies with two diagnostic assays in three of the 516 individuals and with one diagnostic assay in six of the 516 individuals.ConclusionSeroprevalence of CCHFV was between 0.58% and 1.16% in Castile-León, Spain. This is the first study in western Spain that showed circulation of CCHFV in healthy people.es_ES
dc.description.sponsorshipThis study was supported by the Institute of Health Carlos III, ISCIII, Spain (www.isciii.es), grants: RICET RD16/0027/0018 (AM) and RD16/0003/0003 (MPSS), DTS16/00207 (AM), PI16/01784 (PFS), European Union co-financing by FEDER (Fondo Europeo de Desarrollo Regional) ‘Una manera de hacer Europa’.es_ES
dc.language.isoenges_ES
dc.publisherEuropean Centre for Disease Prevention and Control (ECDC) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectCCHFes_ES
dc.subjectCrimean-Congo haemorrhagic feveres_ES
dc.subjectBlood donores_ES
dc.subjectEmerging diseaseses_ES
dc.subjectEpidemiologyes_ES
dc.subjectLaboratoryes_ES
dc.subjectRe-emerging diseaseses_ES
dc.subjectTick-borne diseaseses_ES
dc.subjectViral haemorrhagic feveres_ES
dc.titleCrimean-Congo haemorrhagic fever (CCHF) virus-specific antibody detection in blood donors, Castile-León, Spain, summer 2017 and 2018es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID32183933es_ES
dc.format.volume25es_ES
dc.format.number10es_ES
dc.identifier.doi10.2807/1560-7917.ES.2020.25.10.1900507es_ES
dc.contributor.funderInstituto de Salud Carlos III 
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) 
dc.description.peerreviewedes_ES
dc.identifier.e-issn1560-7917es_ES
dc.relation.publisherversionhttps://doi.org/10.2807/1560-7917.ES.2020.25.10.1900507es_ES
dc.identifier.journalEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletines_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/RICET RD16/0027/0018es_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/RD16/0003/0003es_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/DTS16/00207es_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/PI16/01784es_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Atribución 4.0 Internacional