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dc.contributor.authorGarcía-Pérez, Pablo
dc.contributor.authorEspana, Samuel 
dc.date.accessioned2020-03-30T14:28:12Z
dc.date.available2020-03-30T14:28:12Z
dc.date.issued2020-01-13
dc.identifier.citationEJNMMI Phys. 2020; 7(1):3es_ES
dc.identifier.issn2197-7364es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/9371
dc.description.abstractBACKGROUND: Simultaneous reconstruction of emission and attenuation images in time-of-flight (TOF) positron emission tomography (PET) does not provide a unique solution. In this study, we propose to solve this limitation by including additional information given by a reference object with known attenuation placed outside the patient. Different configurations of the reference object were studied including geometry, material composition, and activity, and an optimal configuration was defined. In addition, this configuration was tested for different timing resolutions and noise levels. RESULTS: The proposed strategy was tested in 2D simulations obtained by forward projection of available PET/CT data and noise was included using Monte Carlo techniques. Obtained results suggest that the optimal configuration corresponds to a water cylinder inserted in the patient table and filled with activity. In that case, mean differences between reconstructed and true images were below 10%. However, better results can be obtained by increasing the activity of the reference object. CONCLUSION: This study shows promising results that might allow to obtain an accurate attenuation map from pure TOF-PET data without prior knowledge obtained from CT, MRI, or transmission scans.es_ES
dc.description.sponsorshipThis work was supported by a grant from the Comunidad de Madrid (2016-T1/TIC-1099). The CNIC is supported by the Instituto de Salud Carlos III (ISCIII); the Ministerio de Ciencia, Innovación y Universidades (MCNU); and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (SEV-2015-0505).es_ES
dc.language.isoenges_ES
dc.publisherSpringerOnees_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAttenuation correctiones_ES
dc.subjectJoint reconstructiones_ES
dc.subjectPositron emission tomographyes_ES
dc.subjectTime of flightes_ES
dc.titleSimultaneous emission and attenuation reconstruction in time-of-flight PET using a reference objectes_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID31932984es_ES
dc.format.volume7es_ES
dc.format.number1es_ES
dc.format.page3es_ES
dc.identifier.doi10.1186/s40658-020-0272-9es_ES
dc.contributor.funderMinisterio de Ciencia, Innovación y Universidades (España)es_ES
dc.contributor.funderInstituto de Salud Carlos III - ISCIIIes_ES
dc.contributor.funderFundación ProCNICes_ES
dc.contributor.funderComunidad de Madrides_ES
dc.description.peerreviewedes_ES
dc.relation.publisherversionhttps://doi.org/10.1186/s40658-020-0272-9es_ES
dc.identifier.journalEJNMMI physicses_ES
dc.repisalud.orgCNICCNIC::Grupos de investigaciónes_ES
dc.repisalud.institucionCNICes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/SEV-2015-0505es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Atribución 4.0 Internacional
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