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dc.contributor.authorRivera-Izquierdo, Mario
dc.contributor.authorMartínez-Ruiz, Virginia
dc.contributor.authorCastillo-Ruiz, Elena Mercedes
dc.contributor.authorManzaneda-Navío, Miriam
dc.contributor.authorPerez-Gomez, Beatriz 
dc.contributor.authorJimenez-Moleon, Jose J.
dc.identifier.citationInt J Environ Res Public Health. 2020 Feb 19;17(4). pii: E1345.es_ES
dc.description.abstractThe International Agency of Research in Cancer (IARC) has recently confirmed shift work as a type 2A carcinogen. The results presented in published epidemiological studies regarding prostate cancer are inconsistent and the association remains controversial. The aims of this study were: (a) to investigate the possible association between shift work and prostate cancer incidence, identifying possible sources of heterogeneity; and (b) to analyze the potential effect of publication bias. A search for cohort and case-control studies published from January 1980 to November 2019 was conducted. The quality of the articles was assessed using the Newcastle-Ottawa Scale. Pooled OR were calculated using random-effects models. Heterogeneity was evaluated using Cochran's Q test and data were stratified by potential sources of heterogeneity. Publication bias was analyzed. Eighteen studies were included. No association was found between rotating/night-shift work and prostate cancer, pooled OR 1.07 (95%CI 0.99 to 1.15), I2 = 45.7%, p = 0.016. Heterogeneity was eliminated when only cohort studies (pooled OR 1.03; 95%CI 0.96 to 1.10; I2 = 18.9%, p = 0.264) or high-quality studies (pooled OR 0.99; 95%CI 0.89 to 1.08; I2 = 0.0%, p = 0.571) were considered. A publication bias was detected. An association between shift work and prostate cancer cannot be confirmed with the available current data. Future analytical studies assessing more objective homogeneous exposure variables still seem necessary.es_ES
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI) es_ES
dc.subjectcircadian disruptiones_ES
dc.subjectheterogeneity analysises_ES
dc.subjectnight workes_ES
dc.subjectoccupational healthes_ES
dc.subjectprostate canceres_ES
dc.subjectrotating shift workes_ES
dc.titleShift Work and Prostate Cancer: An Updated Systematic Review and Meta-Analysises_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.journalInternational journal of environmental research and public healthes_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemologíaes_ES
dc.rights.accessRightsopen accesses_ES

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Atribución 4.0 Internacional
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