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dc.contributor.authorGarcía-Esquinas, Esther 
dc.contributor.authorOrtolá, Rosario
dc.contributor.authorGalan, Iñaki 
dc.contributor.authorSoler-Vila, Hosanna
dc.contributor.authorLaclaustra, Martín
dc.contributor.authorRodríguez-Artalejo, Fernando
dc.date.accessioned2020-02-25T12:00:08Z
dc.date.available2020-02-25T12:00:08Z
dc.date.issued2018
dc.identifier.citationSci Rep. 2018 Jul 31;8(1):11512.es_ES
dc.identifier.issn2045-2322es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/9145
dc.description.abstractThe scarce research on the effects of moderate alcohol consumption on mental health among older adults suggests a protective effect against depression. We prospectively examined the association between patterns of moderate alcohol consumption, depression and psychological distress, using information from 5,299 community-dwelling older adults from the ELSA and Seniors-ENRICA cohorts. A Mediterranean drinking pattern (MDP) was defined as moderate alcohol intake (<40 g/day for men; <24 g/day for women) with a preference for wine and drinking only with meals. Depression was ascertained with the 10-item Geriatric Depression Scale (GDS-10), a self-report of clinically-diagnosed depression, or being on anti-depressant medication (Seniors-ENRICA); and with the 8-item Center for Epidemiologic Studies Depression Scale (CES-D) (ELSA). Psychological distress was assessed with the General Health Questionnaire-12 (GHQ-12). Compared to never drinkers, moderate drinkers showed comparable scores on the ENRICA-GDS-10 (PRR (95%CI): 1.03 (0.84-1.26)), the ENRICA-GHQ-12 (0.88 (0.73-1.06)), the ELSA-CES-D (0.92 (0.79-1.06)) and the ELSA-GHQ-12 (0.75 (0.55-1.01). The MDP was not associated with the GDS-10 or GHQ-12 scores, or with clinically-diagnosed depression; however drinkers with a preference for wine showed an increased number of psychological distress symptoms (1.31 (1.03-1.66)). In conclusion, we found no consistent protective association between moderate alcohol consumption and depression in older adults.es_ES
dc.description.sponsorshipThis work was supported by grant no. 02/2014 from the Plan Nacional sobre Drogas (Ministry of Health of Spain). Additional support was obtained from FIS grants nos. 12/1166 and 16/609 (Instituto de Salud Carlos III, State Secretary of R + D + I and FEDER/FSE); the FRAILOMIC Initiative (European Union FP7 grant agreement 305483-2); the Ageing Trajectories of Health: Longitudinal Opportunities and Synergies (ATHLOS) project (European Union H2020 grant agreement 635316); and the CIBER of Epidemiology and Public Health (CIBERESP). ELSA waves have been funded jointly by UK government departments and the National Institute on Aging, in the USA. The funding agencies had no role in study design, data analysis, interpretation of results, manuscript preparation or in the decision to submit this manuscript for publication. Dr. Laclaustra was supported by Agencia Aragonesa para la Investigación y Desarrollo (ARAID).es_ES
dc.language.isoenges_ES
dc.publisherNature Publishing Group es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshAged es_ES
dc.subject.meshAged, 80 and over es_ES
dc.subject.meshAlcohol Drinking es_ES
dc.subject.meshDepression es_ES
dc.subject.meshDepressive Disorder es_ES
dc.subject.meshFemale es_ES
dc.subject.meshHumans es_ES
dc.subject.meshMale es_ES
dc.subject.meshMental Health es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshProspective Studies es_ES
dc.subject.meshRisk Factors es_ES
dc.subject.meshSpain es_ES
dc.subject.meshSurveys and Questionnaires es_ES
dc.titleModerate alcohol drinking is not associated with risk of depression in older adultses_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID30065286es_ES
dc.format.volume8es_ES
dc.format.number1es_ES
dc.format.page11512es_ES
dc.identifier.doi10.1038/s41598-018-29985-4es_ES
dc.contributor.funderPlan Nacional de Drogas (España) 
dc.contributor.funderInstituto de Salud Carlos III 
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) 
dc.contributor.funderUnión Europea 
dc.description.peerreviewedes_ES
dc.identifier.e-issn2045-2322es_ES
dc.relation.publisherversionhttps://doi.org/10.1038/s41598-018-29985-4es_ES
dc.identifier.journalScientific reportses_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/02/2014es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/12/1166es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/16/609es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/305483-2es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/635316es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/es_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
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