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dc.contributor.author | García-Esquinas, Esther | |
dc.contributor.author | Ortolá, Rosario | |
dc.contributor.author | Galan, Iñaki | |
dc.contributor.author | Soler-Vila, Hosanna | |
dc.contributor.author | Laclaustra, Martín | |
dc.contributor.author | Rodríguez-Artalejo, Fernando | |
dc.date.accessioned | 2020-02-25T12:00:08Z | |
dc.date.available | 2020-02-25T12:00:08Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Sci Rep. 2018 Jul 31;8(1):11512. | es_ES |
dc.identifier.issn | 2045-2322 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/9145 | |
dc.description.abstract | The scarce research on the effects of moderate alcohol consumption on mental health among older adults suggests a protective effect against depression. We prospectively examined the association between patterns of moderate alcohol consumption, depression and psychological distress, using information from 5,299 community-dwelling older adults from the ELSA and Seniors-ENRICA cohorts. A Mediterranean drinking pattern (MDP) was defined as moderate alcohol intake (<40 g/day for men; <24 g/day for women) with a preference for wine and drinking only with meals. Depression was ascertained with the 10-item Geriatric Depression Scale (GDS-10), a self-report of clinically-diagnosed depression, or being on anti-depressant medication (Seniors-ENRICA); and with the 8-item Center for Epidemiologic Studies Depression Scale (CES-D) (ELSA). Psychological distress was assessed with the General Health Questionnaire-12 (GHQ-12). Compared to never drinkers, moderate drinkers showed comparable scores on the ENRICA-GDS-10 (PRR (95%CI): 1.03 (0.84-1.26)), the ENRICA-GHQ-12 (0.88 (0.73-1.06)), the ELSA-CES-D (0.92 (0.79-1.06)) and the ELSA-GHQ-12 (0.75 (0.55-1.01). The MDP was not associated with the GDS-10 or GHQ-12 scores, or with clinically-diagnosed depression; however drinkers with a preference for wine showed an increased number of psychological distress symptoms (1.31 (1.03-1.66)). In conclusion, we found no consistent protective association between moderate alcohol consumption and depression in older adults. | es_ES |
dc.description.sponsorship | This work was supported by grant no. 02/2014 from the Plan Nacional sobre Drogas (Ministry of Health of Spain). Additional support was obtained from FIS grants nos. 12/1166 and 16/609 (Instituto de Salud Carlos III, State Secretary of R + D + I and FEDER/FSE); the FRAILOMIC Initiative (European Union FP7 grant agreement 305483-2); the Ageing Trajectories of Health: Longitudinal Opportunities and Synergies (ATHLOS) project (European Union H2020 grant agreement 635316); and the CIBER of Epidemiology and Public Health (CIBERESP). ELSA waves have been funded jointly by UK government departments and the National Institute on Aging, in the USA. The funding agencies had no role in study design, data analysis, interpretation of results, manuscript preparation or in the decision to submit this manuscript for publication. Dr. Laclaustra was supported by Agencia Aragonesa para la Investigación y Desarrollo (ARAID). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Nature Publishing Group | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject.mesh | Aged | es_ES |
dc.subject.mesh | Aged, 80 and over | es_ES |
dc.subject.mesh | Alcohol Drinking | es_ES |
dc.subject.mesh | Depression | es_ES |
dc.subject.mesh | Depressive Disorder | es_ES |
dc.subject.mesh | Female | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Male | es_ES |
dc.subject.mesh | Mental Health | es_ES |
dc.subject.mesh | Middle Aged | es_ES |
dc.subject.mesh | Prospective Studies | es_ES |
dc.subject.mesh | Risk Factors | es_ES |
dc.subject.mesh | Spain | es_ES |
dc.subject.mesh | Surveys and Questionnaires | es_ES |
dc.title | Moderate alcohol drinking is not associated with risk of depression in older adults | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.identifier.pubmedID | 30065286 | es_ES |
dc.format.volume | 8 | es_ES |
dc.format.number | 1 | es_ES |
dc.format.page | 11512 | es_ES |
dc.identifier.doi | 10.1038/s41598-018-29985-4 | es_ES |
dc.contributor.funder | Plan Nacional de Drogas (España) | |
dc.contributor.funder | Instituto de Salud Carlos III | |
dc.contributor.funder | Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) | |
dc.contributor.funder | Unión Europea | |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 2045-2322 | es_ES |
dc.relation.publisherversion | https://doi.org/10.1038/s41598-018-29985-4 | es_ES |
dc.identifier.journal | Scientific reports | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Epidemiología | es_ES |
dc.repisalud.institucion | ISCIII | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/02/2014 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/12/1166 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/16/609 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/305483-2 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/635316 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/ | es_ES |
dc.rights.accessRights | open access | es_ES |