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dc.contributor.authorJarlier, Vincent
dc.contributor.authorDiaz Högberg, Liselotte
dc.contributor.authorHeuer, Ole E
dc.contributor.authorCampos, Jose 
dc.contributor.authorEckmanns, Tim
dc.contributor.authorGiske, Christian G
dc.contributor.authorGrundmann, Hajo
dc.contributor.authorJohnson, Alan P
dc.contributor.authorKahlmeter, Gunnar
dc.contributor.authorMonen, Jos
dc.contributor.authorPantosti, Annalisa
dc.contributor.authorRossolini, Gian Maria
dc.contributor.authorvan de Sande-Bruinsma, Nienke
dc.contributor.authorVatopoulos, Alkiviadis
dc.contributor.authorŻabicka, Dorota
dc.contributor.authorŽemličková, Helena
dc.contributor.authorMonnet, Dominique L
dc.contributor.authorSimonsen, Gunnar Skov
dc.identifier.citationEuro Surveill. 2019 Aug;24(33).es_ES
dc.description.abstractBackgroundAntibiotic resistance, either intrinsic or acquired, is a major obstacle for treating bacterial infections.AimOur objective was to compare the country-specific species distribution of the four Gram-negative species Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter species and the proportions of selected acquired resistance traits within these species.MethodWe used data reported for 2016 to the European Antimicrobial Resistance Surveillance Network (EARS-Net) by 30 countries in the European Union and European Economic Area.ResultsThe country-specific species distribution varied considerably. While E. coli accounted for 31.9% to 81.0% (median: 69.0%) of all reported isolates, the two most common intrinsically resistant species P. aeruginosa and Acinetobacter spp. combined (PSEACI) accounted for 5.5% to 39.2% of isolates (median: 10.1%). Similarly, large national differences were noted for the percentages of acquired non-susceptibility to third-generation cephalosporins, carbapenems and fluoroquinolones. There was a strong positive rank correlation between the country-specific percentages of PSEACI and the percentages of non-susceptibility to the above antibiotics in all four species (rho > 0.75 for 10 of the 11 pairs of variables tested).ConclusionCountries with the highest proportion of P. aeruginosa and Acinetobacter spp. were also those where the rates of acquired non-susceptibility in all four studied species were highest. The differences are probably related to national differences in antibiotic consumption and infection prevention and control routines.es_ES
dc.description.sponsorshipThe authors acknowledge the work performed by the staff of the participating clinical microbiology laboratories and of the national healthcare services that provided data to EARS-Net.es_ES
dc.publisherEuropean Centre for Disease Prevention and Control (ECDC) es_ES
dc.subjectGram-negative bacillies_ES
dc.subjectAntibiotic resistancees_ES
dc.subjectAntimicrobial resistancees_ES
dc.subjectBacterial infectionses_ES
dc.subjectBloodstream infectiones_ES
dc.titleStrong correlation between the rates of intrinsically antibiotic-resistant species and the rates of acquired resistance in Gram-negative species causing bacteraemia, EU/EEA, 2016es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.journalEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletines_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.rights.accessRightsopen accesses_ES

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