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dc.contributor.authorGullen, Pedro 
dc.contributor.authorVarela, Carmen 
dc.contributor.authorMartínez, Elena Vanessa
dc.contributor.authorGomez-Barroso, Diana
dc.identifier.citationEnviron Int. 2017 May;102:230-235.es_ES
dc.description.abstractBACKGROUND: There is growing concern of how climate change could affect public health, due to the increase number of extreme climate events. Hence, the study of the role that climate events play on the distribution of waterborne diseases, like Hepatitis A, could be key for developing new prevention approaches. OBJECTIVE: To investigate the association between climate factors and Hepatitis A in Spain between 2010 and 2014. METHODS: Weekly Hepatitis A cases between 2010 and 2014 were obtained from the Spanish Epidemiology Surveillance Network. Climate variables (weekly cumulative rainfall, rainy days, storm days and snow days) were obtained from National Climatic Data Center (NOAA satellite and information Service of USA). Each municipality was assigned to the nearest weather station (N=73). A Mixed-Effects Poisson regression was performed to estimate Incidence Rate Ratios (IRR), including a time lag of 2, 3 and 4weeks (most probable incubation period for Hepatitis A). RESULTS: Rainfall higher than 90th percentile (extreme precipitation) was associated with increased number of Hepatitis A cases 2weeks (IRR=1.24 CI 95%=1.09-1.40) and 4weeks after the event (IRR=1.15 CI 95%=1.01-1.30). An extra rainy day increased the risk of Hepatitis A two weeks after (IRR=1.03 CI 95%=1.01-1.05). We found higher risk of Hepatitis A two weeks after each extra storm day (IRR=1.06 CI 95%=1.00-1.12), and lower risk with 3 and 4weeks' lag (IRR=0.93 CI 95%=0.88-0.99 for lag3; IRR=0.94 CI 95%=0.88-0.99 for lag 4). CONCLUSIONS: There is an increased risk of Hepatitis A 2weeks after water-related climate events. Including meteorological information in surveillance systems might improve to develop early prevention strategies for waterborne diseases.es_ES
dc.description.sponsorshipThis study has been funded by Instituto de Salud Carlos III through the project “PI15/01398” (Co-funded by European Regional Development Fund/European Social Fund “Investing in your future”). Pedro Gullón was supported by the Medical Residents program of Spanish Ministry of Health and by the Enrique Nájera grant for Young Epidemiologists (12th edition) awarded by the Sociedad Española de Epidemiología.es_ES
dc.publisherElsevier es_ES
dc.subjectClimate changees_ES
dc.subjectHepatitis Aes_ES
dc.subjectWeather conditionses_ES
dc.subject.meshAdult es_ES
dc.subject.meshFemale es_ES
dc.subject.meshHepatitis A es_ES
dc.subject.meshHumans es_ES
dc.subject.meshIncidence es_ES
dc.subject.meshMale es_ES
dc.subject.meshSpain es_ES
dc.subject.meshYoung Adult es_ES
dc.subject.meshClimate es_ES
dc.subject.meshWeather es_ES
dc.titleAssociation between meteorological factors and hepatitis A in Spain 2010-2014es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.contributor.funderInstituto de Salud Carlos III 
dc.identifier.journalEnvironment internationales_ES
dc.repisalud.centroISCIII::Escuela Nacional de Sanidades_ES
dc.rights.accessRightsopen accesses_ES

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