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dc.contributor.authorCullen, Elizabeth
dc.contributor.authorEvans, David
dc.contributor.authorGriffin, Chris
dc.contributor.authorBurke, Padraig
dc.contributor.authorMannion, Rory
dc.contributor.authorBurns, Damien
dc.contributor.authorFlanagan, Andrew
dc.contributor.authorKellegher, Ann
dc.contributor.authorSchoeters, Greet
dc.contributor.authorGovarts, Eva
dc.contributor.authorBiot, Pierre
dc.contributor.authorCasteleyn, Ludwine
dc.contributor.authorCastaño, Argelia 
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorEsteban-Lopez, Marta 
dc.contributor.authorSchwedler, Gerda
dc.contributor.authorKoch, Holger M
dc.contributor.authorAngerer, Jürgen
dc.contributor.authorKnudsen, Lisbeth E
dc.contributor.authorJoas, Reinhard
dc.contributor.authorJoas, Anke
dc.contributor.authorDumez, Birgit
dc.contributor.authorSepai, Ovnair
dc.contributor.authorExley, Karen
dc.contributor.authorAerts, Dominique
dc.date.accessioned2020-01-16T07:57:09Z
dc.date.available2020-01-16T07:57:09Z
dc.date.issued2017
dc.identifier.citationInt J Environ Res Public Health. 2017 Nov 25;14(12). pii: E1456.es_ES
dc.identifier.issn1660-4601es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/8908
dc.description.abstractBackground: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the 'Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale' (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.es_ES
dc.description.sponsorshipWe would like to acknowledge the funders of the DEMOCOPHES project (LIFE09 ENV/BE/000410) which was jointly financed by the European Commission Programme LIFE and each participating country (http://www.eu-hbm.info/democophes/project-partners). In addition, we would like to thank the COPHES project for providing the operational and scientific framework (European Community’s Seventh Framework Programme—DG Research Grant Agreement Number 244237). Special thanks to all the mothers and children who agreed to participate in the study. In addition the WP team leaders and the national implementation teams, particularly the Irish national team (Catherine Cosgrove, David O’Brien, Rita O’Grady, Niamh McGrath, Anita Larini, Carol Nolan, Gemma McGrane and Sarah Duffy) for support in terms of data collection, analysis, and interpretation. We would like to thank Claire Dunne and Fiona Kavanagh for proof reading and assistance throughout the project, and Padraig Manning, Clinical Librarian and Elaine Scanlon, Library assistant from the HSE library in Steevens’ hospital, Dublin 8 for their assistance in accessing the literature.es_ES
dc.language.isoenges_ES
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectEndocrine disruptorses_ES
dc.subjectExposurees_ES
dc.subjectHuman biomonitoringes_ES
dc.subjectPhthalateses_ES
dc.subject.meshAdult es_ES
dc.subject.meshChild es_ES
dc.subject.meshChild, Preschool es_ES
dc.subject.meshEnvironmental Exposure es_ES
dc.subject.meshEnvironmental Monitoring es_ES
dc.subject.meshEnvironmental Pollutants es_ES
dc.subject.meshFemale es_ES
dc.subject.meshHumans es_ES
dc.subject.meshIreland es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshMothers es_ES
dc.subject.meshPhthalic Acids es_ES
dc.subject.meshPolyvinyl Chloride es_ES
dc.subject.meshRural Population es_ES
dc.subject.meshSurveys and Questionnaires es_ES
dc.subject.meshUrban Population es_ES
dc.titleUrinary Phthalate Concentrations in Mothers and Their Children in Ireland: Results of the DEMOCOPHES Human Biomonitoring Studyes_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID29186834es_ES
dc.format.volume14es_ES
dc.format.number12es_ES
dc.format.page1456es_ES
dc.identifier.doi10.3390/ijerph14121456es_ES
dc.contributor.funderUnión Europea es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1660-4601es_ES
dc.relation.publisherversionhttps://doi.org/10.3390/ijerph14121456es_ES
dc.identifier.journalInternational journal of environmental research and public healthes_ES
dc.repisalud.centroISCIII::Centro Nacional de Sanidad Ambientales_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/LIFE09 ENV/BE/000410es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/European Community’s Seventh Framework Programme—DG Research Grant Agreement Number 244237es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/es_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Atribución 4.0 Internacional