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dc.contributor.authorLatina, Jacqueline
dc.contributor.authorFernandez-Jimenez, Rodrigo 
dc.contributor.authorBansilal, Sameer
dc.contributor.authorSartori, Samantha
dc.contributor.authorVedanthan, Rajesh
dc.contributor.authorLewis, Marcelle
dc.contributor.authorKofler, Claire
dc.contributor.authorHunn, Marilyn
dc.contributor.authorMartin, Francis
dc.contributor.authorBagiella, Emilia
dc.contributor.authorFarkouh, Michael
dc.contributor.authorFuster, Valentin
dc.identifier.citationAm Heart J. 2019; 220:20-28es_ES
dc.description.abstractBACKGROUND: The incidence of cardiovascular (CV) risk factors is increasing globally, with a disproportionate burden in the low and low-middle income countries (L/LMICs). Peer support, as a low-cost lifestyle intervention, has succeeded in managing chronic illness. For global CV risk reduction, limited data exists in LMICs. AIM: The GHP-CHANGE was designed as a community-based randomized trial to test the effectiveness of peer support strategy for CV risk reduction in the island of Grenada, a LMIC. METHODS: We recruited 402 adults from the Grenada Heart Project (GHP) Cohort Study of 2827 subjects with at least two CV risk factors. Subjects were randomized in a 1:1 fashion to a peer-group based intervention group (n = 206) or a self-management control group (n = 196) for 12 months. The primary outcome was the change from baseline in a composite score related to Blood pressure, Exercise, Weight, Alimentation and Tobacco (FBS, Fuster-BEWAT Score), ranging from 0 to 15 (ideal health = 15). Linear mixed-effects models were used to test for intervention effects. RESULTS: Participants mean age was 51.4 years (SD 14.5) years, two-thirds were female, and baseline mean FBS was 8.9 (SD 2.6) and 8.5 (SD 2.6) in the intervention and control group, respectively (P = .152). At post intervention, the mean FBS was higher in the intervention group compared to the control group [9.1 (SD 2.7) vs 8.5 (SD 2.6), P = .028]. When balancing baseline health profile, the between-group difference (intervention vs. control) in the change of FBS was 0.31 points (95% CI: -0.12 to 0.75; P = .154). CONCLUSIONS: The GHP-CHANGE trial showed that a peer-support lifestyle intervention program was feasible; however, it did not demonstrate a significant improvement in the FBS as compared to the control group. Further studies should assess the effects of low-cost lifestyle interventions in LMICs.es_ES
dc.description.sponsorshipThis study was funded by the Louis B Mayer Foundation. VF is a recipient offunding from the American Heart Association under grant No 14SFRN20490315. R.F-J isa recipient of funding from the European Union Horizon 2020 research and innovationprogramme under the Marie Skłodowska-Curie grant agreement No 707642. The CNIC is supported by the Instituto de Salud Carlos III (ISCIII), the Ministerio de Ciencia, Innovación yUniversidades (MCNU) and the Pro CNIC Foundation, and is a Severo Ochoa Center ofExcellence (SEV-2015-0505).es_ES
dc.publisherElsevier es_ES
dc.titleGrenada Heart Project-Community Health ActioN to EncouraGe healthy BEhaviors (GHP-CHANGE): A randomized control peer group-based lifestyle interventiones_ES
dc.typejournal articlees_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.contributor.funderAmerican Heart Association 
dc.contributor.funderLouis B. Mayer Foundation 
dc.contributor.funderUnión Europea. Comisión Europea 
dc.contributor.funderInstituto de Salud Carlos III 
dc.contributor.funderFundación ProCNIC 
dc.contributor.funderMinisterio de Ciencia, Innovación y Universidades (España) 
dc.identifier.journalAmerican heart journales_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Laboratorio Traslacional para la Imagen y Terapia Cardiovasculares_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Imagen Cardiovascular y Estudios Poblacionaleses_ES
dc.rights.accessRightsopen accesses_ES

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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