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dc.contributor.author | Fernandez-Jimenez, Rodrigo | |
dc.contributor.author | Jaslow, Risa | |
dc.contributor.author | Bansilal, Sameer | |
dc.contributor.author | Diaz-Munoz, Raquel | |
dc.contributor.author | Fatterpekar, Monali | |
dc.contributor.author | Santana, Maribel | |
dc.contributor.author | Clarke-Littman, Andrea | |
dc.contributor.author | Latina, Jacqueline | |
dc.contributor.author | Soto, Ana V | |
dc.contributor.author | Hill, Christopher A | |
dc.contributor.author | Al-Kazaz, Mohamed | |
dc.contributor.author | Samtani, Rajeev | |
dc.contributor.author | Vedanthan, Rajesh | |
dc.contributor.author | Giannarelli, Chiara | |
dc.contributor.author | Kovacic, Jason C | |
dc.contributor.author | Bagiella, Emilia | |
dc.contributor.author | Kasarskis, Andrew | |
dc.contributor.author | Fayad, Zahi A | |
dc.contributor.author | Fuster, Valentin | |
dc.date.accessioned | 2020-01-14T13:46:49Z | |
dc.date.available | 2020-01-14T13:46:49Z | |
dc.date.issued | 2020-01-07 | |
dc.identifier.citation | J Am Coll Cardiol. 2020; 75(1):7-14 | es_ES |
dc.identifier.issn | 0735-1097 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/8881 | |
dc.description.abstract | BACKGROUND: The current trends of unhealthy lifestyle behaviors in underserved communities are disturbing. Thus, effective health promotion strategies constitute an unmet need. OBJECTIVES: The purpose of this study was to assess the impact of 2 different lifestyle interventions on parents/caregivers of children attending preschools in a socioeconomically disadvantaged community. METHODS: The FAMILIA (Family-Based Approach in a Minority Community Integrating Systems-Biology for Promotion of Health) study is a cluster-randomized trial involving 15 Head Start preschools in Harlem, New York. Schools, and their children's parents/caregivers, were randomized to receive either an "individual-focused" or "peer-to-peer-based" lifestyle intervention program for 12 months or control. The primary outcome was the change from baseline to 12 months in a composite health score related to blood pressure, exercise, weight, alimentation, and tobacco (Fuster-BEWAT Score [FBS]), ranging from 0 to 15 (ideal health = 15). To assess the sustainability of the intervention, this study evaluated the change of FBS at 24 months. Main pre-specified secondary outcomes included changes in FBS subcomponents and the effect of the knowledge of presence of atherosclerosis as assessed by bilateral carotid/femoral vascular ultrasound. Mixed-effects models were used to test for intervention effects. RESULTS: A total of 635 parents/caregivers were enrolled: mean age 38 ± 11 years, 83% women, 57% Hispanic/Latino, 31% African American, and a baseline FBS of 9.3 ± 2.4 points. The mean within-group change in FBS from baseline to 12 months was ∼0.20 points in all groups, with no overall between-group differences. However, high-adherence participants to the intervention exhibited a greater change in FBS than their low-adherence counterparts: 0.30 points (95% confidence interval: 0.03 to 0.57; p = 0.027) versus 0.00 points (95% confidence interval: -0.43 to 0.43; p = 1.0), respectively. Furthermore, the knowledge by the participant of the presence of atherosclerosis significantly boosted the intervention effects. Similar results were sustained at 24 months. CONCLUSIONS: Although overall significant differences were not observed between intervention and control groups, the FAMILIA trial highlights that high adherence rates to lifestyle interventions may improve health outcomes. It also suggests a potential contributory role of the presentation of atherosclerosis pictures, providing helpful information to improve future lifestyle interventions in adults. | es_ES |
dc.description.sponsorship | AGENCIA FINANCIADORA: The American Heart Association, under grant No 14SFRN20490315, funded this study. R.F-J is a recipient of funding from the European Union Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 707642. The CNIC is supported by the Instituto de Salud Carlos III (ISCIII), the Ministerio de Ciencia, Innovación y Universidades (MCNU) and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (SEV-2015-0505). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Caregivers | es_ES |
dc.subject | Health promotion | es_ES |
dc.subject | Lifestyle | es_ES |
dc.subject | Parents | es_ES |
dc.subject | Vulnerable populations | es_ES |
dc.title | Different Lifestyle Interventions in Adults From Underserved Communities: The FAMILIA Trial | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.identifier.pubmedID | 31726193 | es_ES |
dc.format.volume | 75 | es_ES |
dc.format.number | 1 | es_ES |
dc.format.page | 42-56 | es_ES |
dc.identifier.doi | 10.1016/j.jacc.2019.10.021 | es_ES |
dc.contributor.funder | American Heart Association | |
dc.contributor.funder | Unión Europea. Comisión Europea | |
dc.contributor.funder | Instituto de Salud Carlos III | |
dc.contributor.funder | Ministerio de Ciencia, Innovación y Universidades (España) | |
dc.contributor.funder | Fundación ProCNIC | |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 1558-3597 | es_ES |
dc.relation.publisherversion | https://doi.org/10.1016/j.jacc.2019.10.021 | es_ES |
dc.identifier.journal | Journal of the American College of Cardiology | es_ES |
dc.repisalud.orgCNIC | CNIC::Grupos de investigación::Laboratorio Traslacional para la Imagen y Terapia Cardiovascular | es_ES |
dc.repisalud.orgCNIC | CNIC::Grupos de investigación::Imagen Cardiovascular y Estudios Poblacionales | es_ES |
dc.repisalud.institucion | CNIC | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/SEV-2015-0505 | es_ES |
dc.rights.accessRights | open access | es_ES |