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dc.contributor.authorFernandez-Jimenez, Rodrigo 
dc.contributor.authorJaslow, Risa
dc.contributor.authorBansilal, Sameer
dc.contributor.authorDiaz-Munoz, Raquel
dc.contributor.authorFatterpekar, Monali
dc.contributor.authorSantana, Maribel
dc.contributor.authorClarke-Littman, Andrea
dc.contributor.authorLatina, Jacqueline
dc.contributor.authorSoto, Ana V
dc.contributor.authorHill, Christopher A
dc.contributor.authorAl-Kazaz, Mohamed
dc.contributor.authorSamtani, Rajeev
dc.contributor.authorVedanthan, Rajesh
dc.contributor.authorGiannarelli, Chiara
dc.contributor.authorKovacic, Jason C
dc.contributor.authorBagiella, Emilia
dc.contributor.authorKasarskis, Andrew
dc.contributor.authorFayad, Zahi A
dc.contributor.authorFuster, Valentin 
dc.date.accessioned2020-01-14T13:46:49Z
dc.date.available2020-01-14T13:46:49Z
dc.date.issued2020-01-07
dc.identifier.citationJ Am Coll Cardiol. 2020; 75(1):7-14es_ES
dc.identifier.issn0735-1097es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/8881
dc.description.abstractBACKGROUND: The current trends of unhealthy lifestyle behaviors in underserved communities are disturbing. Thus, effective health promotion strategies constitute an unmet need. OBJECTIVES: The purpose of this study was to assess the impact of 2 different lifestyle interventions on parents/caregivers of children attending preschools in a socioeconomically disadvantaged community. METHODS: The FAMILIA (Family-Based Approach in a Minority Community Integrating Systems-Biology for Promotion of Health) study is a cluster-randomized trial involving 15 Head Start preschools in Harlem, New York. Schools, and their children's parents/caregivers, were randomized to receive either an "individual-focused" or "peer-to-peer-based" lifestyle intervention program for 12 months or control. The primary outcome was the change from baseline to 12 months in a composite health score related to blood pressure, exercise, weight, alimentation, and tobacco (Fuster-BEWAT Score [FBS]), ranging from 0 to 15 (ideal health = 15). To assess the sustainability of the intervention, this study evaluated the change of FBS at 24 months. Main pre-specified secondary outcomes included changes in FBS subcomponents and the effect of the knowledge of presence of atherosclerosis as assessed by bilateral carotid/femoral vascular ultrasound. Mixed-effects models were used to test for intervention effects. RESULTS: A total of 635 parents/caregivers were enrolled: mean age 38 ± 11 years, 83% women, 57% Hispanic/Latino, 31% African American, and a baseline FBS of 9.3 ± 2.4 points. The mean within-group change in FBS from baseline to 12 months was ∼0.20 points in all groups, with no overall between-group differences. However, high-adherence participants to the intervention exhibited a greater change in FBS than their low-adherence counterparts: 0.30 points (95% confidence interval: 0.03 to 0.57; p = 0.027) versus 0.00 points (95% confidence interval: -0.43 to 0.43; p = 1.0), respectively. Furthermore, the knowledge by the participant of the presence of atherosclerosis significantly boosted the intervention effects. Similar results were sustained at 24 months. CONCLUSIONS: Although overall significant differences were not observed between intervention and control groups, the FAMILIA trial highlights that high adherence rates to lifestyle interventions may improve health outcomes. It also suggests a potential contributory role of the presentation of atherosclerosis pictures, providing helpful information to improve future lifestyle interventions in adults.es_ES
dc.description.sponsorshipAGENCIA FINANCIADORA: The American Heart Association, under grant No 14SFRN20490315, funded this study. R.F-J is a recipient of funding from the European Union Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 707642. The CNIC is supported by the Instituto de Salud Carlos III (ISCIII), the Ministerio de Ciencia, Innovación y Universidades (MCNU) and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (SEV-2015-0505).es_ES
dc.language.isoenges_ES
dc.publisherElsevier es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCaregiverses_ES
dc.subjectHealth promotiones_ES
dc.subjectLifestylees_ES
dc.subjectParentses_ES
dc.subjectVulnerable populationses_ES
dc.titleDifferent Lifestyle Interventions in Adults From Underserved Communities: The FAMILIA Triales_ES
dc.typejournal articlees_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.identifier.pubmedID31726193es_ES
dc.format.volume75es_ES
dc.format.number1es_ES
dc.format.page42-56es_ES
dc.identifier.doi10.1016/j.jacc.2019.10.021es_ES
dc.contributor.funderAmerican Heart Association 
dc.contributor.funderUnión Europea. Comisión Europea 
dc.contributor.funderInstituto de Salud Carlos III 
dc.contributor.funderMinisterio de Ciencia, Innovación y Universidades (España) 
dc.contributor.funderFundación ProCNIC 
dc.description.peerreviewedes_ES
dc.identifier.e-issn1558-3597es_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.jacc.2019.10.021es_ES
dc.identifier.journalJournal of the American College of Cardiologyes_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Laboratorio Traslacional para la Imagen y Terapia Cardiovasculares_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Imagen Cardiovascular y Estudios Poblacionaleses_ES
dc.repisalud.institucionCNICes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/SEV-2015-0505es_ES
dc.rights.accessRightsopen accesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Attribution-NonCommercial-NoDerivatives 4.0 Internacional