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dc.contributor.authorBarrero, Maria Jose 
dc.date.accessioned2019-10-16T07:49:31Z
dc.date.available2019-10-16T07:49:31Z
dc.date.issued2017-05-23
dc.identifier.citationInt J Mol Sci. 2017;18(6). pii: E1108.es_ES
dc.identifier.issn1422-0067es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/8496
dc.descriptionThe CNIO- Lilly Epigenetics Laboratory is supported by Eli Lilly and Company.es_ES
dc.description.abstractRecently, immunotherapeutic approaches have shown impressive responses in a subset of cancer patients. However, the rate of success is low and a large percentage of treated patients do not experience clinical benefits. Therefore, additional strategies are needed to improve responses and select responsive patients. Emerging data suggest that epigenetic drugs can improve the responses to immunotherapy. Understanding the mechanisms of resistance to immunotherapy and the epigenetic events that take place during immune evasion is critical to providing a rational combined use of immunotherapies and epigenetic drugs. This review focuses in the epigenetic mechanisms involved in the responses to immunotherapy and how current drugs that target epigenetic regulators impact on them.es_ES
dc.language.isoenges_ES
dc.publisherMPDIes_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectcanceres_ES
dc.subjectepigeneticses_ES
dc.subjectimmunotherapyes_ES
dc.subject.meshEpigenesis, Genetices_ES
dc.subject.meshHumans es_ES
dc.subject.meshImmunotherapy es_ES
dc.subject.meshNeoplasms es_ES
dc.titleEpigenetic Strategies to Boost Cancer Immunotherapieses_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.identifier.pubmedID28545238es_ES
dc.format.volume18es_ES
dc.format.number6es_ES
dc.format.page1108es_ES
dc.identifier.doi10.3390/ijms18061108es_ES
dc.contributor.funderLilly
dc.description.peerreviewedes_ES
dc.identifier.e-issn1422-0067es_ES
dc.relation.publisherversionhttps://doi.org/10.3390/ijms18061108.es_ES
dc.identifier.journalInternational journal of molecular scienceses_ES
dc.repisalud.institucionCNIOes_ES
dc.repisalud.orgCNIOCNIO::Grupos de investigación::Antiguos CNIOes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Atribución-NoComercial-CompartirIgual 4.0 Internacional
This item is licensed under a: Atribución-NoComercial-CompartirIgual 4.0 Internacional