Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/8389
A novel community driven software for functional enrichment analysis of extracellular vesicles data
Pathan, Mohashin | Keerthikumar, Shivakumar | Chisanga, David | Alessandro, Riccardo | Ang, Ching-Seng | Askenase, Philip | Batagov, Arsen O | Benito-Martin, Alberto | Camussi, Giovanni | Clayton, Aled | Collino, Federica | Di Vizio, Dolores | Falcon-Perez, Juan Manuel | Fonseca, Pedro | Fonseka, Pamali | Fontana, Simona | Gho, Yong Song | Hendrix, An | Hoen, Esther Nolte-'t | Iraci, Nunzio | Kastaniegaard, Kenneth | Kislinger, Thomas | Kowal, Joanna | Kurochkin, Igor V | Leonardi, Tommaso | Liang, Yaxuan | Llorente, Alicia | Lunavat, Taral R | Maji, Sayantan | Monteleone, Francesca | Øverbye, Anders | Panaretakis, Theocharis | Patel, Tushar | Peinado Selgas, Hector CNIO | Pluchino, Stefano | Principe, Simona | Ronquist, Goran | Royo, Felix | Sahoo, Susmita | Spinelli, Cristiana | Stensballe, Allan | Théry, Clotilde | van Herwijnen, Martijn J C | Wauben, Marca | Welton, Joanne L | Zhao, Kening | Mathivanan, Suresh
J Extracell Vesicles. 2017 ;6(1):1321455
Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture "what the community needs in a tool". Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.
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