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dc.contributor.authorCasas Flecha, Inmaculada 
dc.contributor.authorAvellón, Ana 
dc.contributor.authorMosquera Gutierrez, Maria del Mar 
dc.contributor.authorJabado, O
dc.contributor.authorEchevarria, Juan Emilio 
dc.contributor.authorCampos, R H
dc.contributor.authorRewers, M
dc.contributor.authorPerez-Breña, Pilar 
dc.contributor.authorLipkin, W I
dc.contributor.authorPalacios, G
dc.date.accessioned2019-08-14T07:33:13Z
dc.date.available2019-08-14T07:33:13Z
dc.date.issued2005-12
dc.identifier.citationJ Clin Microbiol. 2005 Dec;43(12):6176-82.es_ES
dc.identifier.issn0095-1137es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/8278
dc.description.abstractHere we present a system for adenovirus detection and genotyping based on PCR amplification and phylogenetic analysis of a conserved hexon gene fragment. The system was validated using 157 sequences (86 previously typed and 71 clinical samples) and correctly identified species and serotype in 100% and 84% of sequences, respectively. Known associations between specific serotypes and clinical syndromes are verified. Possible new associations are described to allow further independent testing.es_ES
dc.description.sponsorshipWe acknowledge technical assistance from Manuela López-Valero in the Respiratory Viruses Laboratory, CNM, ISCIII, Majadahonda, Madrid, Spain. We thank Neil Renwick for his critical reviewing of the manuscript and helpful comments. We also thank the reviewers for their constructive criticism and helpful suggestions on the initial draft. This work was supported by grants from the National Institutes of Health (AI51292, AI55466, AI056118, and U54AI057158-Northeast Biodefense Center), the Ellison Medical Foundation, and ISCIII (MPY 1251/00 and MPY 1018/04).es_ES
dc.language.isoenges_ES
dc.publisherAmerican Society for Microbiology (ASM) es_ES
dc.type.hasVersionAMes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshAdenovirus Infections, Human es_ES
dc.subject.meshAdenoviruses, Human es_ES
dc.subject.meshAdolescent es_ES
dc.subject.meshAdult es_ES
dc.subject.meshCapsid Proteins es_ES
dc.subject.meshChild es_ES
dc.subject.meshChild, Preschool es_ES
dc.subject.meshDNA, Viral es_ES
dc.subject.meshGenome, Viral es_ES
dc.subject.meshHumans es_ES
dc.subject.meshInfant es_ES
dc.subject.meshInfant, Newborn es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshMolecular Sequence Data es_ES
dc.subject.meshPhylogeny es_ES
dc.subject.meshPolymerase Chain Reaction es_ES
dc.subject.meshSerotyping es_ES
dc.subject.meshSequence Analysis, DNA es_ES
dc.titleMolecular identification of adenoviruses in clinical samples by analyzing a partial hexon genomic regiones_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.identifier.pubmedID16333124es_ES
dc.format.volume43es_ES
dc.format.number12es_ES
dc.format.page6176-82es_ES
dc.identifier.doi10.1128/JCM.43.12.6176-6182.2005es_ES
dc.contributor.funderInstituto de Salud Carlos III 
dc.relation.publisherversionhttps://doi.org/10.1128/JCM.43.12.6176-6182.2005es_ES
dc.identifier.journalJournal of clinical microbiologyes_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/AI51292es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/AI55466es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/AI056118es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/U54AI057158es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/MPY 1251/00es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/MPY 1018/04es_ES
dc.rights.accessRightsopen accesses_ES


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