Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/8096
Proposing a Parkinson's disease-specific tremor scale from the MDS-UPDRS
Forjaz, Maria Joao ISCIII | Ayala, Alba ISCIII | Testa, Claudia M | Bain, Peter G | Elble, Rodger | Haubenberger, Dietrich | Rodriguez-Blazquez, Carmen ISCIII | Deuschl, Günther | Martinez-Martin, Pablo ISCIII
Mov Disord. 2015 Jul;30(8):1139-43.
BACKGROUND: This article proposes an International Parkinson and Movement Disorder Society (MDS)-UPDRS tremor-based scale and describes its measurement properties, with a view to developing an improved scale for assessing tremor in Parkinson's disease (PD). METHODS: This was a cross-sectional, multicenter study of 435 PD patients. Rasch analysis was performed on the 11 MDS-UPDRS tremor items. Construct validity, precision, and test-retest reliability were also analyzed. RESULTS: After some modifications, which included removal of an item owing to redundancy, the obtained MDS-UPDRS tremor scale showed moderate reliability, unidimensionality, absence of differential item functioning, satisfactory convergent validity with medication, and better precision than the raw sum score. However, the scale displayed a floor effect and a need for more items measuring lower levels of tremor. CONCLUSIONS: The MDS-UPDRS tremor scale provides linear scores that can be used to assess tremor in PD in a valid, reliable way. The scale might benefit from modifications and studies that analyze its responsiveness.
Aged | Cross-Sectional Studies | Female | Humans | Male | Middle Aged | Parkinson Disease | Psychometrics | Reproducibility of Results | Tremor | Severity of Illness Index
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