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dc.contributor.authorHuetos, Olga 
dc.contributor.authorBartolome, Monica 
dc.contributor.authorAragones, Nuria 
dc.contributor.authorCervantes-Amat, Marta 
dc.contributor.authorEsteban-Lopez, Marta 
dc.contributor.authorRuiz-Moraga, M
dc.contributor.authorPerez-Gomez, Beatriz 
dc.contributor.authorCalvo, E
dc.contributor.authorVila, M
dc.contributor.authorCastaño, Argelia 
dc.identifier.citationSci Total Environ. 2014 Sep 15;493:834-44.es_ES
dc.description.abstractThis manuscript presents the levels of six indicator polychlorinated biphenyl (PCB) congeners (IUPAC nos. 28, 52, 101, 138, 153 and 180) in the serum of 1880 individuals from a representative sample of the Spanish working population recruited between March 2009 and July 2010. Three out of the six PCBs studied (180, 153 and 138) were quantified in more than 99% of participants. PCB 180 was the highest contributor, followed by PCBs 153 and 138, with relative abundances of 42.6%, 33.2% and 24.2%, respectively. In contrast, PCBs 28 and 52 were detected in only 1% of samples, whereas PCB 101 was detectable in 6% of samples. The geometric mean (GM) for ΣPCBs138/153/180 was 135.4 ng/g lipid (95% CI: 121.3-151.2 ng/g lipid) and the 95th percentile was 482.2 ng/g lipid. Men had higher PCB blood concentrations than women (GMs 138.9 and 129.9 ng/g lipid respectively). As expected, serum PCB levels increased with age and frequency of fish consumption, particularly in those participants younger than 30 years of age. The highest levels we found were for participants from the Basque Country, whereas the lowest concentrations were found for those from the Canary Islands. The Spanish population studied herein had similar levels to those found previously in Greece and southern Italy, lower levels than those in France and central Europe, and higher PCB levels than those in the USA, Canada and New Zealand. This paper provides the first baseline information regarding PCB exposure in the Spanish adult population on a national scale. The results will allow us to establish reference levels, follow temporal trends and identify high-exposure groups, as well as monitor implementation of the Stockholm Convention in Spain.es_ES
dc.description.sponsorshipThis work was funded as part of a research agreement between the Spanish Ministry of Agriculture, Food and the Environment n° EG042007 and the Institute of Health Carlos III (project nos. SEG 1251/07 and 1210/10). The authors would like to thank S. González for the technical assistance, F. Cutanda for the helpful advice, and Silvia Gómez; the volunteers of BIOAMBIENT.ES and healthcare staff from the Societies for Prevention of IBERMUTUAMUR, MUTUALIA, MCPREVENCIÓN, MUGATRA, UNIMAT PREVENCIÓN, and PREVIMAC.es_ES
dc.publisherElsevier es_ES
dc.subjectHuman biomonitoringes_ES
dc.subjectPolychlorinated biphenyls (PCBs)es_ES
dc.subjectWorking populationes_ES
dc.subject.meshAdult es_ES
dc.subject.meshEnvironmental Exposure es_ES
dc.subject.meshEnvironmental Pollutants es_ES
dc.subject.meshFemale es_ES
dc.subject.meshHumans es_ES
dc.subject.meshMale es_ES
dc.subject.meshPolychlorinated Biphenyls es_ES
dc.subject.meshSpain es_ES
dc.titleSerum PCB levels in a representative sample of the Spanish adult population: the BIOAMBIENT.ES projectes_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución-NoComercial-SinObraDerivada 4.0 Internacional*
dc.contributor.funderInstituto de Salud Carlos III 
dc.contributor.funderMinisterio de Agricultura, Alimentación y Medio Ambiente (España) 
dc.identifier.journalThe Science of the total environmentes_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemologíaes_ES
dc.repisalud.centroISCIII::Centro Nacional de Sanidad Ambientales_ES
dc.rights.accessRightsopen accesses_ES

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Atribución-NoComercial-SinObraDerivada 4.0 Internacional
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