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dc.contributor.authorHuertas, Jesus R.
dc.contributor.authorCasuso, Rafael A.
dc.contributor.authorHernansanz-Agustín, Pablo
dc.contributor.authorCogliati, Sara
dc.identifier.citationOxid Med Cell Longev. 2019; 2019:7058350es_ES
dc.description.abstractSkeletal muscles require the proper production and distribution ofenergy to sustain their work. To ensure this requirement is met, mitochondria form large networks within skeletal muscle cells, and during exercise, they can enhance their functions. In the present review, we discuss recent findings on exercise-induced mitochondrial adaptations. We emphasize the importance ofmitochondrial biogenesis, morphological changes, and increases in respiratory supercomplex formation as mechanisms triggered by exercise that may increase the function of skeletal muscles. Finally, we highlight the possible effects of nutraceutical compounds on mitochondrial performance during exercise and outline the use of exercise as a therapeutic tool in noncommunicable disease prevention. The resulting picture shows that the modulation of mitochondrial activity by exercise is not only fundamental for physical performance but also a key point for whole-organism well-being.es_ES
dc.description.sponsorshipThe CNIC is supported by the Instituto de Salud Carlos III (ISCIII), the Ministerio de Ciencia, Innovación y Universidades (MCNU), and the Pro CNIC Foundation and is a Severo Ochoa Center of Excellence (SEV-2015-0505).es_ES
dc.publisherHindawi es_ES
dc.titleStay Fit, Stay Young: Mitochondria in Movement: The Role of Exercise in the New Mitochondrial Paradigmes_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.contributor.funderInstituto de Salud Carlos III 
dc.contributor.funderMinisterio de Ciencia, Innovación y Universidades (España) 
dc.contributor.funderFundación ProCNIC 
dc.identifier.journalOxidative Medicine and Cellular Longevityes_ES
dc.repisalud.orgCNICCNIC::Grupos de investigación::Genética Funcional del Sistema de Fosforilación Oxidativaes_ES
dc.rights.accessRightsopen accesses_ES

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Atribución 4.0 Internacional
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