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dc.contributor.authorJohnson, Catherine Owens
dc.contributor.authorNguyen, Minh
dc.contributor.authorRoth, Gregory A
dc.contributor.authorNichols, Emma
dc.contributor.authorAlam, Tahiya
dc.contributor.authorAbate, Degu
dc.contributor.authorAbd-Allah, Foad
dc.contributor.authorAbdelalim, Ahmed
dc.contributor.authorAbraha, Haftom Niguse
dc.contributor.authorAbu-Rmeileh, Niveen ME
dc.contributor.authorAdebayo, Oladimeji M
dc.contributor.authorGrosso, Giuseppe
dc.contributor.authorGuo, Yuming
dc.contributor.authorGupta, Rajeev
dc.contributor.authorHaj-Mirzaian, Arvin
dc.contributor.authorHaj-Mirzaian, Arya
dc.contributor.authorKazemeini, Hossein
dc.contributor.authorHamidi, Samer
dc.contributor.authorHankey, Graeme J.
dc.contributor.authorHassen, Hamid Yimam
dc.contributor.authorRahim, Fakher
dc.contributor.authorWolfe, Charles D A
dc.contributor.authorHay, Simon I.
dc.contributor.authorHegazy, Mohamed I
dc.contributor.authorHeidari, Behnam
dc.contributor.authorHerial, Nabeel A
dc.contributor.authorHosseini, Mohammad Ali
dc.contributor.authorHostiuc, Sorin
dc.contributor.authorIrvani, Seyed Sina Naghibi
dc.contributor.authorKefale, Adane Teshome
dc.contributor.authorIslam, Sheikh Mohammed Shariful
dc.contributor.authorJahanmehr, Nader
dc.contributor.authorWondafrash, Dawit Zewdu
dc.contributor.authorAlvis-Guzman, Nelson
dc.contributor.authorJavanbakht, Mehdi
dc.contributor.authorKhader, Yousef Saleh
dc.contributor.authorKhalil, Ibrahim A.
dc.contributor.authorKhan, Ejaz Ahmad
dc.contributor.authorKhang, Young-Ho
dc.contributor.authorAgarwal, Gina
dc.contributor.authorKhubchandani, Jagdish
dc.contributor.authorKim, Daniel
dc.contributor.authorKim, Yun Jin
dc.contributor.authorXu, Gelin
dc.contributor.authorKisa, Adnan
dc.contributor.authorJha, Ravi Prakash
dc.contributor.authorKivimäki, Mika
dc.contributor.authorKoyanagi, Ai
dc.contributor.authorKrishnamurthi, Rita K
dc.contributor.authorKumar, G Anil
dc.contributor.authorLafranconi, Alessandra
dc.contributor.authorLewington, Sarah
dc.contributor.authorAgrawal, Sutapa
dc.contributor.authorLi, Shanshan
dc.contributor.authorYadollahpour, Ali
dc.contributor.authorLo, Warren David
dc.contributor.authorLopez, Alan D
dc.contributor.authorRahimi, Kazem
dc.contributor.authorLorkowski, Stefan
dc.contributor.authorLotufo, Paulo A.
dc.contributor.authorMackay, Mark T
dc.contributor.authorMajdan, Marek
dc.contributor.authorMajdzadeh, Reza
dc.contributor.authorMajeed, Azeem
dc.contributor.authorMalekzadeh, Reza
dc.contributor.authorYamada, Tomohide
dc.contributor.authorAichour, Amani Nidhal
dc.contributor.authorManafi, Navid
dc.contributor.authorMansournia, Mohammad Ali
dc.contributor.authorRahimi-Movaghar, Vafa
dc.contributor.authorMehndiratta, Man Mohan
dc.contributor.authorMehta, Varshil
dc.contributor.authorMengistu, Getnet
dc.contributor.authorMeretoja, Atte
dc.contributor.authorMeretoja, Tuomo J
dc.contributor.authorMiazgowski, Bartosz
dc.contributor.authorAwasthi, Ashish
dc.contributor.authorMiazgowski, Tomasz
dc.contributor.authorMiller, Ted R
dc.contributor.authorAichour, Ibtihel
dc.contributor.authorMirrakhimov, Erkin M
dc.contributor.authorRahman, Mahfuzar
dc.contributor.authorMohajer, Bahram
dc.contributor.authorMohammad, Yousef
dc.contributor.authorMohammadoo-khorasani, Milad
dc.contributor.authorMohammed, Shafiu
dc.contributor.authorMohebi, Farnam
dc.contributor.authorYatsuya, Hiroshi
dc.contributor.authorMokdad, Ali H
dc.contributor.authorMokhayeri, Yaser
dc.contributor.authorMoradi, Ghobad
dc.contributor.authorMorawska, Lidia
dc.contributor.authorAichour, Miloud Taki Eddine
dc.contributor.authorRahman, Muhammad Aziz
dc.contributor.authorMoreno Velásquez, Ilais
dc.contributor.authorMousavi, Seyyed Meysam
dc.contributor.authorMuhammed, Oumer Sada S
dc.contributor.authorMuruet, Walter
dc.contributor.authorYimer, Ebrahim M
dc.contributor.authorNaderi, Mehdi
dc.contributor.authorNaghavi, Mohsen
dc.contributor.authorNaik, Gurudatta
dc.contributor.authorNascimento, Bruno Ramos
dc.contributor.authorNegoi, Ruxandra Irina
dc.contributor.authorNguyen, Cuong Tat
dc.contributor.authorReis, Cesar
dc.contributor.authorAlahdab, Fares
dc.contributor.authorNguyen, Long Hoang
dc.contributor.authorNirayo, Yirga Legesse
dc.contributor.authorYonemoto, Naohiro
dc.contributor.authorNorrving, Bo
dc.contributor.authorNoubiap, Jean Jacques
dc.contributor.authorOfori-Asenso, Richard
dc.contributor.authorOgbo, Felix Akpojene
dc.contributor.authorOlagunju, Andrew T
dc.contributor.authorOlagunju, Tinuke O
dc.contributor.authorOwolabi, Mayowa Ojo
dc.contributor.authorRemuzzi, Giuseppe
dc.contributor.authorPandian, Jeyaraj Durai
dc.contributor.authorAli, Raghib
dc.contributor.authorKanchan, Tanuj
dc.contributor.authorPatel, Shanti
dc.contributor.authorRenzaho, Andre M.N.
dc.contributor.authorRicci, Stefano
dc.contributor.authorRoberts, Nicholas L S
dc.contributor.authorRobinson, Stephen R
dc.contributor.authorJonas, Jost B.
dc.contributor.authorAnber, Nahla Hamed
dc.contributor.authorRoever, Leonardo
dc.contributor.authorRoshandel, Gholamreza
dc.contributor.authorSabbagh, Parisa
dc.contributor.authorPerico, Norberto
dc.contributor.authorSafari, Hosein
dc.contributor.authorSafari, Saeed
dc.contributor.authorSafiri, Saeid
dc.contributor.authorSahebkar, Amirhossein
dc.contributor.authorSalehi Zahabi, Saleh
dc.contributor.authorSamy, Abdallah M
dc.contributor.authorJozwiak, Jacek Jerzy
dc.contributor.authorSantalucia, Paola
dc.contributor.authorAnjomshoa, Mina
dc.contributor.authorSantos, Itamar S
dc.contributor.authorYousefifard, Mahmoud
dc.contributor.authorSantos, João Vasco
dc.contributor.authorSantric Milicevic, Milena M
dc.contributor.authorSartorius, Benn
dc.contributor.authorSawant, Arundhati R
dc.contributor.authorSchutte, Aletta Elisabeth
dc.contributor.authorSepanlou, Sadaf G.
dc.contributor.authorShafieesabet, Azadeh
dc.contributor.authorJürisson, Mikk
dc.contributor.authorShaikh, Masood Ali
dc.contributor.authorShams-Beyranvand, Mehran
dc.contributor.authorYu, Chuanhua
dc.contributor.authorArabloo, Jalal
dc.contributor.authorSheikh, Aziz
dc.contributor.authorSheth, Kevin N.
dc.contributor.authorShibuya, Kenji
dc.contributor.authorShigematsu, Mika
dc.contributor.authorShin, Min-Jeong
dc.contributor.authorShiue, Ivy
dc.contributor.authorSiabani, Soraya
dc.contributor.authorKahsay, Amaha
dc.contributor.authorSobaih, Badr Hasan
dc.contributor.authorZaidi, Zoubida
dc.contributor.authorSposato, Luciano A.
dc.contributor.authorSutradhar, Ipsita
dc.contributor.authorArauz, Antonio
dc.contributor.authorSylaja, PN
dc.contributor.authorSzoeke, Cassandra E I
dc.contributor.authorTe Ao, Braden James
dc.contributor.authorTemsah, Mohamad-Hani
dc.contributor.authorTemsah, Omar
dc.contributor.authorThrift, Amanda G
dc.contributor.authorKalani, Rizwan
dc.contributor.authorZamani, Mohammad
dc.contributor.authorTonelli, Marcello
dc.contributor.authorTopor-Madry, Roman
dc.contributor.authorTran, Bach Xuan
dc.contributor.authorTran, Khanh Bao
dc.contributor.authorÄrnlöv, Johan
dc.contributor.authorTruelsen, Thomas Clement
dc.contributor.authorTsadik, Afewerki Gebremeskel
dc.contributor.authorUllah, Irfan
dc.contributor.authorUthman, Olalekan A
dc.contributor.authorVaduganathan, Muthiah
dc.contributor.authorZarghi, Afshin
dc.contributor.authorKalkonde, Yogeshwar
dc.contributor.authorValdez, Pascual R
dc.contributor.authorVasankari, Tommi Juhani
dc.contributor.authorVasanthan, Rajagopalan
dc.contributor.authorVenketasubramanian, Narayanaswamy
dc.contributor.authorVosoughi, Kia
dc.contributor.authorArora, Amit
dc.contributor.authorVu, Giang Thu
dc.contributor.authorWaheed, Yasir
dc.contributor.authorWeiderpass, Elisabete
dc.contributor.authorZhang, Yunquan
dc.contributor.authorWeldegwergs, Kidu Gidey
dc.contributor.authorKamil, Teshome Abegaz
dc.contributor.authorWesterman, Ronny
dc.contributor.authorZodpey, Sanjay
dc.contributor.authorBanach, Maciej
dc.contributor.authorFeigin, Valery L
dc.contributor.authorVos, Theo
dc.contributor.authorPiradov, Michael A
dc.contributor.authorKarch, André
dc.contributor.authorMurray, Christopher J L
dc.contributor.authorBarboza, Miguel A
dc.contributor.authorBarker-Collo, Suzanne Lyn
dc.contributor.authorBärnighausen, Till Winfried
dc.contributor.authorBasu, Sanjay
dc.contributor.authorBelachew, Abate Bekele
dc.contributor.authorBelayneh, Yaschilal Muche
dc.contributor.authorBennett, Derrick A.
dc.contributor.authorBensenor, Isabela M
dc.contributor.authorPolinder, Suzanne
dc.contributor.authorBhattacharyya, Krittika
dc.contributor.authorAdeoye, Abiodun Moshood
dc.contributor.authorBiadgo, Belete
dc.contributor.authorBijani, Ali
dc.contributor.authorBikbov, Boris
dc.contributor.authorBin Sayeed, Muhammad Shahdaat
dc.contributor.authorButt, Zahid A
dc.contributor.authorCahuana-Hurtado, Lucero
dc.contributor.authorCarrero, Juan J
dc.contributor.authorCarvalho, Félix
dc.contributor.authorPostma, Maarten J
dc.contributor.authorCastañeda-Orjuela, Carlos A
dc.contributor.authorCastro, Franz
dc.contributor.authorKarimi, Narges
dc.contributor.authorCatala-Lopez, Ferran 
dc.contributor.authorChaiah, Yazan
dc.contributor.authorChiang, Peggy Pei-Chia
dc.contributor.authorChoi, Jee-Young J
dc.contributor.authorChristensen, Hanne
dc.contributor.authorChu, Dinh-Toi
dc.contributor.authorCortinovis, Monica
dc.contributor.authorPoustchi, Hossein
dc.contributor.authorDamasceno, Albertino Antonio Moura
dc.contributor.authorDandona, Lalit
dc.contributor.authorDandona, Rakhi
dc.contributor.authorKarimi-Sari, Hamidreza
dc.contributor.authorDaryani, Ahmad
dc.contributor.authorDavletov, Kairat
dc.contributor.authorde Courten, Barbora
dc.contributor.authorDe la Cruz-Góngora, Vanessa
dc.contributor.authorDegefa, Meaza Girma
dc.contributor.authorDharmaratne, Samath Dhamminda
dc.contributor.authorPrakash, V
dc.contributor.authorDiaz, Daniel
dc.contributor.authorDubey, Manisha
dc.contributor.authorDuken, Eyasu Ejeta
dc.contributor.authorEdessa, Dumessa
dc.contributor.authorKasaeian, Amir
dc.contributor.authorEndres, Matthias
dc.contributor.authorFARAON, EMERITO JOSE A
dc.contributor.authorFarzadfar, Farshad
dc.contributor.authorFernandes, Eduarda
dc.contributor.authorFischer, Florian
dc.contributor.authorQorbani, Mostafa
dc.contributor.authorFlor, Luisa Sorio
dc.contributor.authorGanji, Morsaleh
dc.contributor.authorGebre, Abadi Kahsu
dc.contributor.authorGebremichael, Teklu Gebrehiwo
dc.contributor.authorGeta, Birhanu
dc.contributor.authorKassa, Tesfaye Dessale
dc.contributor.authorGezae, Kebede Embaye
dc.contributor.authorGill, Paramjit Singh
dc.contributor.authorGnedovskaya, Elena V.
dc.contributor.authorGómez-Dantés, Hector
dc.contributor.authorRafiei, Alireza
dc.contributor.authorGoulart, Alessandra C
dc.date.accessioned2019-05-20T07:47:12Z
dc.date.available2019-05-20T07:47:12Z
dc.date.issued2019-05
dc.identifier.citationLancet Neurol. 2019;18(5):439-458.es_ES
dc.identifier.issn1474-4422es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/7590
dc.description.abstractBACKGROUND: Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, year, and location to provide information to health systems and policy makers on more than 300 causes of disease and injury, including stroke. The results presented here are the estimates of burden due to overall stroke and ischaemic and haemorrhagic stroke from GBD 2016. METHODS: We report estimates and corresponding uncertainty intervals (UIs), from 1990 to 2016, for incidence, prevalence, deaths, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs). DALYs were generated by summing YLLs and YLDs. Cause-specific mortality was estimated using an ensemble modelling process with vital registration and verbal autopsy data as inputs. Non-fatal estimates were generated using Bayesian meta-regression incorporating data from registries, scientific literature, administrative records, and surveys. The Socio-demographic Index (SDI), a summary indicator generated using educational attainment, lagged distributed income, and total fertility rate, was used to group countries into quintiles. FINDINGS: In 2016, there were 5·5 million (95% UI 5·3 to 5·7) deaths and 116·4 million (111·4 to 121·4) DALYs due to stroke. The global age-standardised mortality rate decreased by 36·2% (-39·3 to -33·6) from 1990 to 2016, with decreases in all SDI quintiles. Over the same period, the global age-standardised DALY rate declined by 34·2% (-37·2 to -31·5), also with decreases in all SDI quintiles. There were 13·7 million (12·7 to 14·7) new stroke cases in 2016. Global age-standardised incidence declined by 8·1% (-10·7 to -5·5) from 1990 to 2016 and decreased in all SDI quintiles except the middle SDI group. There were 80·1 million (74·1 to 86·3) prevalent cases of stroke globally in 2016; 41·1 million (38·0 to 44·3) in women and 39·0 million (36·1 to 42·1) in men. INTERPRETATION: Although age-standardised mortality rates have decreased sharply from 1990 to 2016, the decrease in age-standardised incidence has been less steep, indicating that the burden of stroke is likely to remain high. Planned updates to future GBD iterations include generating separate estimates for subarachnoid haemorrhage and intracerebral haemorrhage, generating estimates of transient ischaemic attack, and including atrial fibrillation as a risk factor. FUNDING: Bill & Melinda Gates Foundation.es_ES
dc.description.sponsorshipBill & Melinda Gates Foundationes_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.meshStroke es_ES
dc.subject.meshGlobal Burden of Disease es_ES
dc.titleGlobal, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016es_ES
dc.typeArtículoes_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.identifier.pubmedID30871944es_ES
dc.format.volume18es_ES
dc.format.number5es_ES
dc.format.page439-458es_ES
dc.identifier.doi10.1016/S1474-4422(19)30034-1es_ES
dc.contributor.funderBill & Melinda Gates Foundationes_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1474-4465es_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1016/ S1474-4422(19)30034-1es_ES
dc.identifier.journalThe Lancet. Neurologyes_ES
dc.repisalud.centroISCIII::Escuela Nacional de Sanidad::Departamento de Planificación y Economía de la Saludes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
This item is licensed under a: Attribution-NonCommercial-NoDerivatives 4.0 Internacional