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dc.contributor.authorCastellote, Juan Manuel 
dc.contributor.authorValls-Solé, J
dc.date.accessioned2019-04-03T08:27:09Z
dc.date.available2019-04-03T08:27:09Z
dc.date.issued2019-03-01
dc.identifier.citationSci Rep. 2019 Mar 1;9(1):3264.es_ES
dc.identifier.issn2045-2322es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/7432
dc.description.abstractA combined assessment tool for the perceptual-motor aspects of pain processing will be valuable to clinicians. Fifteen healthy subjects were exposed to contact-heat stimulation (Pathway, Medoc, Israel) to assess perception through a simple task (motor response or conscious appraisal of the time the stimulus was felt) or with a dual task (both responses). The outcome measure was the temporal relationship between contact heat evoked potentials (CHEPS), reaction time (RT) and conscious awareness (AW). There were different temporal profiles for CHEPs, RT and AW to changes in stimulus intensity, AW being the least affected. Performing the dual task led to a significantly more pronounced effect on RT than on AW, while CHEPS were not influenced by task performance. Our results support the dissociation between physiological, behavioral and cognitive events elicited by nociceptive stimuli. The time of conscious appraisal of stimulus occurrence is a complementary information to other responses such as evoked potentials or behavioral tasks. The combined assessment of physiological and behavioral aspects of pain processing may provide clinicians with information on the different paths followed by nociceptive afferent inputs in the central nervous system.es_ES
dc.description.sponsorshipThe study was carried out in part thanks to funds from grants: PI1300526 from Fondo de Investigaciones Sanitarias to J. Valls-Sole, ESPY-112/18 from Instituto de Salud Carlos III and Grant PRX12/00349 from Government of Spain to J. M. Castellote.es_ES
dc.language.isoenges_ES
dc.publisherNature Researches_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleTemporal relationship between perceptual and physiological events triggered by nociceptive heat stimulies_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID30824733es_ES
dc.format.volume9es_ES
dc.format.number1es_ES
dc.format.page3264es_ES
dc.identifier.doi10.1038/s41598-019-39509-3es_ES
dc.contributor.funderFondo de Investigaciones Sanitarias
dc.contributor.funderInstituto de Salud Carlos III - ISCIII
dc.description.peerreviewedes_ES
dc.identifier.e-issn2045-2322es_ES
dc.relation.publisherversionhttps://doi.org/10.1038/s41598-019-39509-3es_ES
dc.identifier.journalScientific reportses_ES
dc.repisalud.centroISCIII::Escuela Nacional de Medicina del Trabajoes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Atribución 4.0 Internacional
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