Show simple item record

dc.contributor.authorSuarez-Rodriguez, Berta 
dc.contributor.authorLopez-Abente, Gonzalo 
dc.contributor.authorMartínez, Carmen
dc.contributor.authorNavarro, Carmen
dc.contributor.authorTormo, Maria José
dc.contributor.authorRosso, Stefano
dc.contributor.authorSchraub, Simon
dc.contributor.authorGafà, Lorenzo
dc.contributor.authorSancho-Garnier, Hélène
dc.contributor.authorWechsler, Janine
dc.contributor.authorZanetti, Roberto
dc.identifier.citationBMC Public Health. 2007 Jul 26;7:180.es_ES
dc.description.abstractBACKGROUND: Non-melanoma skin cancer (NMSC) is the most frequent tumour among Caucasian populations worldwide. Among the risk factors associated with this tumour, there are host-related factors and several environmental agents. A greater likelihood of high exposure to physical agents (with the exception of solar radiation) and chemical agents depends on the work setting. Our objective is to evaluate the role of occupational exposures in NMSC, with special emphasis on risk factors other than solar radiation and skin type. METHODS: We analysed 1585 cases (1333 basal cell carcinoma (BCC) and 183 squamous cell carcinoma (SCC)) and 1507 controls drawn from the Helios-I multicenter study. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using logistic regression mixed models. RESULTS: For NMSC as a whole (both histological types), miners and quarrymen, secondary education teachers, and masons registered excess risk, regardless of exposure to solar radiation and skin type (OR 7.04, 95% CI 2.44-20.31; OR 1.75, 95% CI 1.05-2.89 and OR 1.54, 95% CI 1.04-2.27, respectively). Frequency of BCC proved higher among railway engine drivers and firemen (OR 4.55; 95% CI 0.96-21.57), specialised farmers (OR 1.65; 95% CI 1.05-2.59) and salesmen (OR 3.02; 95% CI 1.05-2.86), in addition to miners and quarrymen and secondary education teachers (OR 7.96; 95% CI 2.72-23.23 and OR 1.76; 95% CI 1.05-2.94 respectively). The occupations that registered a higher risk of SCC (though not of BCC) were those involving direct contact with livestock, construction workers not elsewhere classified (OR 2.95, 95% CI 1.12-7.74), stationary engine and related equipment operators not elsewhere classified (OR 5.31, 95% CI 1.13-21.04) and masons (OR 2.55, 95% CI 1.36-4.78). CONCLUSION: Exposure to hazardous air pollutants, arsenic, ionizing radiations and burns may explain a good part of the associations observed in this study. The Helios study affords an excellent opportunity for further in-depth study of physical and chemical agents and NMSC based on matrices of occupational exposure.es_ES
dc.description.sponsorshipThis study was financed in part by the Spanish Network for Cooperative Research in Epidemiology and Public Health (Red de Centros de Epidemiología y Salud Pública-RCESP) (FIS-C03/09).es_ES
dc.publisherBioMed Central (BMC) es_ES
dc.subject.meshAdult es_ES
dc.subject.meshAge Distribution es_ES
dc.subject.meshAged es_ES
dc.subject.meshCarcinoma, Basal Cell es_ES
dc.subject.meshCarcinoma, Squamous Cell es_ES
dc.subject.meshCase-Control Studies es_ES
dc.subject.meshCausality es_ES
dc.subject.meshEurope es_ES
dc.subject.meshFemale es_ES
dc.subject.meshHumans es_ES
dc.subject.meshLogistic Models es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshOccupational Exposure es_ES
dc.subject.meshOccupations es_ES
dc.subject.meshRisk Factors es_ES
dc.subject.meshSex Distribution es_ES
dc.subject.meshSkin Neoplasms es_ES
dc.titleOccupation and skin cancer: the results of the HELIOS-I multicenter case-control studyes_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.contributor.funderInstituto de Salud Carlos III 
dc.identifier.journalBMC public healthes_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemologíaes_ES
dc.rights.accessRightsopen accesses_ES

Files in this item

Acceso Abierto

This item appears in the following Collection(s)

Show simple item record

Atribución 4.0 Internacional
This item is licensed under a: Atribución 4.0 Internacional