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dc.contributor.author | Fuente, Luis de la | |
dc.contributor.author | Rosales-Statkus, Maria-Elena | |
dc.contributor.author | Hoyos, Juan | |
dc.contributor.author | Pulido, Jose | |
dc.contributor.author | Santos, Sara | |
dc.contributor.author | Bravo, Maria Jose | |
dc.contributor.author | Barrio, Gregorio | |
dc.contributor.author | Fernandez-Balbuena, Sonia | |
dc.contributor.author | Belza Egozcue, Maria Jose | |
dc.date.accessioned | 2018-12-05T18:19:39Z | |
dc.date.available | 2018-12-05T18:19:39Z | |
dc.date.issued | 2012-10-08 | |
dc.identifier.citation | PLoS One. 2012;7(10):e46555. | es_ES |
dc.identifier.issn | 1932-6203 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/6768 | |
dc.description.abstract | OBJECTIVE: Availability of over-the-counter rapid HIV tests could improve access to testing those reluctant or unable to use current services. We aimed to evaluate the feasibility of HIV self-testing using a finger-stick whole-blood rapid test (Determine™ HIV Combo) to detect both antigen and antibody. METHODS: Before being tested, 313 participants in a street-based testing program were given adapted instructions and a test kit, and performed the self-test without supervision. These participants, together with another 207 who performed supervised self-testing, received additional instructions on how to interpret the test results shown in six colour photos and filled out a questionnaire. Logistic regression and generalized estimating equations (GEE) were used in the statistical analysis. RESULTS: About 8.0% (95%CI:4.8%-11.2%) obtained an invalid self-test. An invalid result was inversely associated with male participants who had sex with men (OR=0.3;95%CI:0.1-1.0). Of the 3111 photos interpreted,4.9% (95%CI:4.1-5.7) were incorrect. Only 1.1% (95%CI:0.3-1.8) of the positive results were interpreted as negative. Age 30 or older (OR=2.1; 95%CI:1.2-3.7), having been born in Latin America (OR=1.6; 95%CI:1.1-2.2),and not having university education (OR=2.1;95%CI:1.2-3.7) were associated with misinterpreting test results in the GEE. Participant's perceptions of both their proficiency when conducting the test and interpretation were related with actual outcomes. Most participants (83.9%) were more motivated than before to use the self-test in the future, and 51.7% would pay >10 Euros for the test if it was sold in pharmacies. CONCLUSIONS: This is the first study showing that blood-based self-testing with current technology is feasible in HIV-negative participants demanding the test and without prior training or supervision. Bearing in mind that it was conducted under difficult weather conditions and using a complex kit, over-the-counter tests could be a feasible option to complement current diagnostic strategies. More studies are needed to accommodate technology, minimise interpretation mistakes and provide on-line support. | es_ES |
dc.description.sponsorship | This study was funded by Fundación para la Investigación y Prevención del Sida en España (FIPSE: 36634/07) and by the Fondo de Investigación Sanitaria (FIS:PI09/9074). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Public Library of Science (PLOS) | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject.mesh | AIDS Serodiagnosis | es_ES |
dc.subject.mesh | Adult | es_ES |
dc.subject.mesh | Female | es_ES |
dc.subject.mesh | Humans | es_ES |
dc.subject.mesh | Male | es_ES |
dc.subject.mesh | Self Care | es_ES |
dc.title | Are participants in a street-based HIV testing program able to perform their own rapid test and interpret the results? | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Atribución 4.0 Internacional | * |
dc.identifier.pubmedID | 23056342 | es_ES |
dc.format.volume | 7 | es_ES |
dc.format.number | 10 | es_ES |
dc.format.page | e46555 | es_ES |
dc.identifier.doi | 10.1371/journal.pone.0046555 | es_ES |
dc.contributor.funder | Fundación para la Investigación y la Prevención del Sida en España | |
dc.contributor.funder | Instituto de Salud Carlos III | |
dc.description.peerreviewed | Sí | es_ES |
dc.identifier.e-issn | 1932-6203 | es_ES |
dc.relation.publisherversion | https://doi.org/10.1371/journal.pone.0046555 | es_ES |
dc.identifier.journal | PloS one | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Epidemiología | es_ES |
dc.repisalud.centro | ISCIII::Escuela Nacional de Sanidad | |
dc.repisalud.institucion | ISCIII | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ES/PI09/9074 | es_ES |
dc.rights.accessRights | open access | es_ES |