Show simple item record

dc.contributor.authorHerrador, Zaida 
dc.contributor.authorRivas, Eva
dc.contributor.authorGherasim, Alin Manuel 
dc.contributor.authorGomez-Barroso, Diana 
dc.contributor.authorGarcía, Jezabel
dc.contributor.authorBenito, Agustin 
dc.contributor.authorAparicio, Pilar
dc.identifier.citationPLoS Negl Trop Dis. 2015;9(4):e0003710.es_ES
dc.description.abstractAfter the United States, Spain comes second in the list of countries receiving migrants from Latin America, and, therefore, it is the European country with the highest expected number of infected patients of Chagas disease. We have studied the National Health System's Hospital Discharge Records Database (CMBD) in order to describe the disease evolution from 1997 to 2011 in Spain. We performed a retrospective descriptive study using CMBD information on hospitalizations including Chagas disease. Data was divided in two periods with similar length in time: 1997-2004 and 2005-2011. Hospitalization rates were calculated and clinical characteristics were described. We used multivariable logistic regression to calculate adjusted odds-ratio (aOR) for the association between various conditions and being hospitalized with organ affectation. A total of 1729 hospitalization records were identified. Hospitalization rates for the two periods were 18 and 242.8/100000 population, respectively. The median age was 35 years (range 0-87), 74% were female and the 16-45 age-group was mostly represented (69.8%). Overall, 23.4% hospitalizations included the diagnosis of Chagas disease with organ complications. Being male [aOR: 1.3 (1.00-1.77)], aged 45 and 64 years [aOR: 2.59 (1.42-4.71)], and a median hospitalization cost above 3,065 euro [aOR: 2.03 (3.73-7.86)] were associated with hospitalizations with organ affectation. Since 2005, the number of detected infections increased in Spain. The predominant patients' profile (asymptomatic women at fertile age) and the conditions associated with organ affectation underlines the need for increased efforts towards the early detection of T cruzi.es_ES
dc.description.sponsorshipWe would like to thank the General Sub-direction of the Institute for Health Information, Spanish Ministry of Health, Social Services and Equality, for providing the information on which this study is based. Corresponding author's affiliation center belongs to the Network Biomedical Research on Tropical Diseases (RICET in Spanish): RD12/0018/0001.es_ES
dc.publisherPublic Library of Sciencees_ES
dc.subject.meshAge Factors es_ES
dc.subject.meshChagas Disease es_ES
dc.subject.meshDatabases, Factuales_ES
dc.subject.meshFemale es_ES
dc.subject.meshHospitalization es_ES
dc.subject.meshHumans es_ES
dc.subject.meshLatin America es_ES
dc.subject.meshLogistic Models es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshOdds Ratio es_ES
dc.subject.meshPrevalence es_ES
dc.subject.meshRetrospective Studies es_ES
dc.subject.meshRisk Factors es_ES
dc.subject.meshSex Factors es_ES
dc.subject.meshSpain es_ES
dc.subject.meshTransients and Migrants es_ES
dc.titleUsing hospital discharge database to characterize Chagas disease evolution in Spain: there is a need for a systematic approach towards disease detection and controles_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.journalPLoS neglected tropical diseaseses_ES
dc.repisalud.centroISCIII::Centro Nacional de Medicina Tropicales_ES
dc.rights.accessRightsopen accesses_ES

Files in this item

Acceso Abierto

This item appears in the following Collection(s)

Show simple item record

Atribución 4.0 Internacional
This item is licensed under a: Atribución 4.0 Internacional