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dc.contributor.authorDiaz-Jimenez, Julio 
dc.contributor.authorArroyo, Virginia
dc.contributor.authorOrtiz Burgos, Cristina 
dc.contributor.authorCarmona-Alferez, Rocio 
dc.contributor.authorLinares-Gil, Cristina 
dc.date.accessioned2018-10-08T17:22:14Z
dc.date.available2018-10-08T17:22:14Z
dc.date.issued2016
dc.identifier.citationPLoS One. 2016 Oct 27;11(10):e0164741.es_ES
dc.identifier.issn1932-6203es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/6471
dc.description.abstractOBJECTIVE: Exposure to pollutants during pregnancy has been related to adverse birth outcomes. LBW can give rise to lifelong impairments. Prematurity is the leading cause of LBW, yet few studies have attempted to analyse how environmental factors can influence LBW in infants who are not premature. This study therefore sought to analyse the influence of air pollution, noise levels and temperature on LBW in non-premature births in Madrid during the period 2001-2009. METHODS: Ecological time-series study to assess the impact of PM2.5, NO2 and O3 concentrations, noise levels, and temperatures on LBW among non-premature infants across the period 2001-2009. Our analysis extended to infants having birth weights of 1,500 g to 2,500 g (VLBW) and less than 1,500 g (ELBW). Environmental variables were lagged until 37 weeks with respect to the date of birth, and cross-correlation functions were used to identify explaining lags. Results were quantified using Poisson regression models. RESULTS: Across the study period 298,705 births were registered in Madrid, 3,290 of which had LBW; of this latter total, 1,492 were non-premature. PM2.5 was the only pollutant to show an association with the three variables of LBW in non-premature births. This association occurred at around the third month of gestation for LBW and VLBW (LBW: lag 23 and VLBW: lag 25), and at around the eighth month of gestation for ELBW (lag 6). Leqd was linked to LBW at lag zero. The RR of PM2.5 on LBW was 1.01 (1.00 1.03). The RR of Leqd on LBW was 1.09 (0.99 1.19)(p<0.1). CONCLUSIONS: The results obtained indicate that PM2.5 had influence on LBW. The adoption of measures aimed at reducing the number of vehicles would serve to lower pregnant women's exposure. In the case of noise should be limited the exposure to high levels during the final weeks of pregnancy.es_ES
dc.description.sponsorshipThe author(s) received no specific funding for this work.es_ES
dc.language.isoenges_ES
dc.publisherPublic Library of Science (PLOS) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.meshAir Pollution es_ES
dc.subject.meshCities es_ES
dc.subject.meshEnvironmental Exposure es_ES
dc.subject.meshFemale es_ES
dc.subject.meshHumans es_ES
dc.subject.meshInfant, Extremely Low Birth Weight es_ES
dc.subject.meshInfant, Very Low Birth Weight es_ES
dc.subject.meshNitrogen Dioxide es_ES
dc.subject.meshNoise es_ES
dc.subject.meshOzone es_ES
dc.subject.meshParticulate Matter es_ES
dc.subject.meshPregnancy es_ES
dc.subject.meshPremature Birth es_ES
dc.subject.meshRisk es_ES
dc.subject.meshSpain es_ES
dc.subject.meshTemperature es_ES
dc.subject.meshInfant, Low Birth Weight es_ES
dc.titleEffect of Environmental Factors on Low Weight in Non-Premature Births: A Time Series Analysises_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID27788159es_ES
dc.format.volume11es_ES
dc.format.number10es_ES
dc.format.pagee0164741es_ES
dc.identifier.doi10.1371/journal.pone.0164741es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1932-6203es_ES
dc.relation.publisherversionhttps://doi.org/10.1371/journal.pone.0164741es_ES
dc.identifier.journalPloS onees_ES
dc.repisalud.centroISCIII::Escuela Nacional de Sanidades_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
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