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dc.contributor.authorLuquin, Maria-Rosario
dc.contributor.authorKulisevsky, Jaime
dc.contributor.authorMartinez-Martin, Pablo 
dc.contributor.authorMir, Pablo
dc.contributor.authorTolosa, Eduardo S.
dc.date.accessioned2018-03-27T09:53:44Z
dc.date.available2018-03-27T09:53:44Z
dc.date.issued2017-01-23
dc.identifier.citationParkinsons Dis. 2017; 2017:4047392es_ES
dc.identifier.issn2090-8083es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/5793
dc.description.abstractTo date, no consensus exists on the key factors for diagnosing advanced Parkinson disease (APD). To obtain consensus on the definition of APD, we performed a prospective, multicenter, Spanish nationwide, 3-round Delphi study (CEPA study). An ad hoc questionnaire was designed with 33 questions concerning the relevance of several clinical features for APD diagnosis. In the first-round, 240 neurologists of the Spanish Movement Disorders Group participated in the study. The results obtained were incorporated into the questionnaire and both, results and questionnaire, were sent out to and fulfilled by 26 experts in Movement Disorders. Review of results from the second-round led to a classification of symptoms as indicative of "definitive," "probable," and "possible" APD. This classification was confirmed by 149 previous participating neurologists in a third-round, where 92% completely or very much agreed with the classification. Definitive symptoms of APD included disability requiring help for the activities of daily living, presence of motor fluctuations with limitations to perform basic activities of daily living without help, severe dysphagia, recurrent falls, and dementia. These results will help neurologists to identify some key factors in APD diagnosis, thus allowing users to categorize the patients for a homogeneous recognition of this condition.es_ES
dc.language.isoenges_ES
dc.publisherHindawi Publishing Corporationes_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleConsensus on the Definition of Advanced Parkinson’s Disease: A Neurologists-Based Delphi Study (CEPA Study)es_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID28239501es_ES
dc.format.volume2017es_ES
dc.format.page4047392es_ES
dc.identifier.doi10.1155/2017/4047392es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn2042-0080es_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1155/2017/4047392es_ES
dc.identifier.journalParkinson's Diseasees_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemología::Área de Epidemiología Aplicadaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Atribución 4.0 Internacional
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