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dc.contributor.authorHernando Sebastian, Victoria 
dc.contributor.authorAlejos, Belén 
dc.contributor.authorMontero, Marta
dc.contributor.authorPérez-Elias, MªJesús
dc.contributor.authorBlanco, José Ramón
dc.contributor.authorGiner, Livia
dc.contributor.authorGómez-Sirvent, Juan Luis
dc.contributor.authorIribarren, Jose Antonio
dc.contributor.authorBernal, Enrique
dc.contributor.authorBolúmar, Francisco
dc.identifier.citationMedicine (Baltimore). 2017;96(5):e5991es_ES
dc.description.abstractThe aim of this study is to examine the reproductive history of human immunodeficiency virus (HIV)-positive women, before and after HIV diagnosis, to describe the characteristics of women with pregnancies after HIV diagnosis, and to assess the prevalence of mother-to-child transmission.A cross-sectional study was performed among women within reproductive ages (18-49) selected from the cohort in the Spanish AIDS Research Network (CoRIS). A descriptive analysis of the pregnancy outcomes was made according to women's serostatus at the moment of pregnancy and association of women's characteristics with having pregnancy after HIV diagnosis was evaluated using logistic regression models.Overall, 161 women were interviewed; of them, 86% had been pregnant at least once and 39% after HIV diagnosis. There were 347 pregnancies, 29% of them occurred after HIV diagnosis and in these, 20% were miscarriages and 29% were voluntary termination of pregnancy. There were 3 cases of mother-to-child transmission among the 56 children born from HIV-positive mothers; in these cases, women were diagnosed during delivery. Having a pregnancy after HIV diagnosis was more likely when the younger women were at the time of diagnosis: odds ratio (OR) = 1.29 (95% confidence interval 0.40-4.17) for 25 to 29 years old, OR = 0.59 (0.15-2.29) for 30 to 34 years old, OR = 0.14 (0.03-0.74) for ≥35 years old, compared with those <25 years at diagnosis, who were diagnosed for ≥5 years (OR = 5.27 [1.71-16.18]), who received antiretroviral treatment at some point (OR = 9.38 [1.09-80.45]), and who received information on reproductive health (OR = 4.32 [1.52-12.26]).An important number of pregnancies occurred after HIV diagnosis, reflecting a desire for motherhood in these women. Reproductive and sexual health should be tackled in medical follow-ups.es_ES
dc.publisherWolters Kluwer es_ES
dc.subjectHIV infectiones_ES
dc.titleReproductive history before and after HIV diagnosis: A cross-sectional study in HIV-positive women in Spain.es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.contributor.funderFundación para la Investigación y la Prevención del Sida en España 
dc.contributor.funderInstituto de Salud Carlos III 
dc.repisalud.centroISCIII::Centro Nacional de Epidemologíaes_ES
dc.rights.accessRightsopen accesses_ES

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