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dc.contributor.authorCoffeng, Jennifer K.
dc.contributor.authorvan der Ploeg, Hidde P.
dc.contributor.authorCastellano, Jose Maria 
dc.contributor.authorFernandez-Alvira, Juan Miguel 
dc.contributor.authorIbanez, Borja 
dc.contributor.authorGarcia-Lunar, Ines 
dc.contributor.authorvan der Beek, Allard J.
dc.contributor.authorFernandez-Ortiz, Antonio 
dc.contributor.authorMocoroa, Agustin
dc.contributor.authorGarcia-Leal, Laura 
dc.contributor.authorCardenas, Evelyn 
dc.contributor.authorRojas, Carolina 
dc.contributor.authorMartinez-Castro, Maria I. 
dc.contributor.authorSantiago-Sacristan, Silvia 
dc.contributor.authorFernandez-Gallardo, Miriam 
dc.contributor.authorMendiguren, Jose M
dc.contributor.authorBansilal, Sameer
dc.contributor.authorvan Mechelen, Willem
dc.contributor.authorFuster, Valentin 
dc.date.accessioned2017-10-20T10:33:50Z
dc.date.available2017-10-20T10:33:50Z
dc.date.issued2017
dc.identifierISI:000396389000017
dc.identifier.citationAm Heart J. 2017; 184:121-132
dc.identifier.issn0002-8703
dc.identifier.urihttp://hdl.handle.net/20.500.12105/5164
dc.description.abstractBackground Cardiovascular disease (CVD) is the leading cause of death worldwide. With atherosclerosis as the underlying cause for many CVD events, prevention or reduction of subclinical atherosclerotic plaque burden (SAPB) through a healthier lifestyle may have substantial public health benefits. Objective The objective was to describe the protocol of a randomized controlled trial investigating the effectiveness of a 30-month worksite-based lifestyle program aimed to promote cardiovascular health in participants having a high or a low degree of SAPB compared with standard care. Methods We will conduct a randomized controlled trial including middle-aged bank employees from the Progression of Early Subclinical Atherosclerosis cohort, stratified by SAPB (high SAPB n = 260, low SAPB n = 590). Within each stratum, participants will be randomized 1:1 to receive a lifestyle program or standard care. The program consists of 3 elements: (a) 12 personalized lifestyle counseling sessions using Motivational Interviewing over a 30-month period, (b) a wrist-worn physical activity tracker, and (c) a sit-stand workstation. Primary outcome measure is a composite score of blood pressure, physical activity, sedentary time, body weight, diet, and smoking (ie, adapted Fuster-BEWAT score) measured at baseline and at 1-, 2-, and 3-year follow-up. Conclusions The study will provide insights into the effectiveness of a 30-month worksite-based lifestyle program to promote cardiovascular health compared with standard care in participants with a high or low degree of SAPB.
dc.description.sponsorshipTANSNIP-PESA is funded by Fundacion Centro Nacional de Investigaciones Cardiovasculares Carlos III with support from an Investigator Sponsor Study grant to Icahn School of Medicine from AstraZeneca. PESA is funded by Fundacion Centro Nacional de Investigaciones Cardiovasculares Carlos III and Grupo Santander. The CNIC is supported by the Spanish Ministry of Economy and Competitiveness (MINECO) and the Pro-CNIC Foundation, and is a Severo Ochoa Center of Excellence (MINECO award SEV-2015-0505). The funders have not been involved in the design and conduct of the study, nor were they involved in the drafting of the manuscript and its final content.
dc.language.isoeng
dc.publisherMOSBY-ELSEVIER
dc.relation.isversionofPublisher's version
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPHYSICAL-ACTIVITY
dc.subjectSUBCLINICAL ATHEROSCLEROSIS
dc.subjectMULTIPLE IMPUTATION
dc.subjectSEDENTARY BEHAVIORS
dc.subjectCOST-EFFECTIVENESS
dc.subjectMETAANALYSIS
dc.subjectQUESTIONNAIRE
dc.subjectWORKPLACE
dc.subjectADULTS
dc.subjectTIME
dc.titleA 30-month worksite-based lifestyle program to promote cardiovascular health in middle-aged bank employees: Design of the TANSNIP-PESA randomized controlled trial
dc.typeArtículo
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.identifier.pubmedID28224926
dc.format.volume184
dc.identifier.doi10.1016/j.ahj.2016.11.002
dc.contributor.funderAstraZeneca
dc.contributor.funderBanco Santander
dc.contributor.funderMinisterio de Economía y Competitividad (MINECO)
dc.contributor.funderFundación ProCNIC
dc.description.peerreviewed
dc.identifier.e-issn1097-5330
dc.relation.publisherversionhttps://doi.org/10.1016/j.ahj.2016.11.002
dc.identifier.journalAmerican Heart Journal
dc.repisalud.orgCNICCNIC::Grupos de investigación::Laboratorio Traslacional para la Imagen y Terapia Cardiovascular
dc.repisalud.orgCNICCNIC::Grupos de investigación::Imagen Cardiovascular y Estudios Poblacionales
dc.repisalud.institucionCNIC
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/SEV-2015-0505es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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