Unidad Funcional de Investigación de Enfermedades Crónicas (UFIEC) : 
Collections in this community
Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy
Alzheimer's disease is a proteinopathy characterized by accumulation of hyperphosphorylated Tau and β-amyloid. Autophagy is a physiological process by which aggregated proteins and damaged organelles are eliminated through lysosomal digestion. Autophagy deficiency has been demonstrated in Alzheimer's pa...
Ocoxin Modulates Cancer Stem Cells and M2 Macrophage Polarization in Glioblastoma
Glioblastoma (GBM) is the most common and devastating primary brain tumor. The presence of cancer stem cells (CSCs) has been linked to their therapy resistance. Molecular and cellular components of the tumor microenvironment also play a fundamental role in the aggressiveness of these...
Novel Functions of the Neurodegenerative-Related Gene Tau in Cancer
The analysis of global and comparative genomics between different diseases allows us to understand the key biological processes that explain the etiology of these pathologies. We have used this type of approach to evaluate the expression of several neurodegeneration-related genes on the ...