El Centro Nacional de Medicina Tropical se crea por orden del 27 de diciembre de 2001 (publicado en BOE del 11 de enero de 2002) para responder a la creciente movilidad internacional (inmigración y viajeros) y también por la mayor presencia española en programas de cooperación internacional, con el objetivo de reforzar la asistencia, investigación y docencia en enfermedades tropicales y establecer programas de cooperación científico-técnica, con países donde existen estas patologías.

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Relapses versus reinfections in patients coinfected with Leishmania infantum and human immunodeficiency virus type 1 

In the Mediterranean basin, Leishmania infantum is a major opportunistic parasite in people with acquired immunodeficiency syndrome (AIDS), and up to 9% of the patients with AIDS suffer from newly acquired or reactivated visceral leishmaniasis. Distinguishing between reinfections and relapses in th...

Preventing chronic malnutrition in children under 2 years in rural Angola (MuCCUA trial): protocol for the economic evaluation of a three-arm community cluster randomised controlled trial 

Introduction: Chronic malnutrition is a serious problem in southern Angola with a prevalence of 49.9% and 37.2% in the provinces of Huila and Cunene, respectively. The MuCCUA (Mother and Child Chronic Undernutrition in Angola) trial is a community-based randomised controlled trial (c-RCT) which aim...

Nutrition knowledge and practices in children under two years of age in Huila, Angola 

Background: The 2021 UN report indicated 149 million children under 5 years suffering malnutrition. African continent has the highest prevalence of stunting. Angola has a persistent nutritional crisis. Improving child-feeding practices is essential to ensure good nutrition. This is the preliminary ...

Lessons from COVID-19 for behavioural and communication interventions to enhance vaccine uptake 

The Covid pandemic has yielded new insights into psychological vaccine acceptance factors. This knowledge serves as a basis for behavioral and communication interventions that can increase vaccination readiness for other diseases.

Screening for K13-Propeller Mutations Associated with Artemisinin Resistance in Plasmodium falciparum in Yambio County (Western Equatoria State, South Sudan) 

Artemisinin-combined treatments are the recommended first-line treatment of Plasmodium falciparum malaria, but they are being threatened by emerging artemisinin resistance. Mutations in pfk13 are the principal molecular marker for artemisinin resistance. This study characterizes the presence of mut...

Rural-Urban Inequities in Tuberculosis-Related Practices in Equatorial Guinea 

Background: Tuberculosis (TB) is one of the leading causes of mortality from a single infectious disease agent. Equatorial Guinea is a country with high estimated TB incidence in 2021 (275 cases per 100,000 population) and low TB case detection (42%). Early diagnosis and prompt treatment are crucia...

Mycobacterium tuberculosis Sub-Lineage 4.2.2/SIT149 as Dominant Drug-Resistant Clade in Northwest Ethiopia 2020-2022: In-silico Whole-Genome Sequence Analysis 

Introduction: Drug resistance (DR) in Mycobacterium tuberculosis complex (MTBC) is mainly associated with certain lineages and varies across regions and countries. The Beijing genotype is the leading resistant lineage in Asia and western countries. M. tuberculosis (Mtb) (sub) lineages responsible f...

Association Between Pandemic Fatigue and Disease Knowledge, Attitudes, Concerns, and Vaccination Intention at Two Key Moments of the COVID-19 Pandemic 

Objective: This study aimed to describe the change in knowledge, attitudes, concerns, perceptions, preventive practices, and vaccination intention at two key time points of the COVID-19 pandemic and to assess whether these changes varied by level of pandemic fatigue. Methods: Data included in this ...

Tuberculosis Knowledge, Attitudes, and Practice in Middle- and Low-Income Countries: A Systematic Review 

Tuberculosis (TB) is the leading cause of death from an infectious agent in the world. Most tuberculosis cases are concentrated in low- and middle-income countries. The aim of this study is to better understand tuberculosis-related knowledge about TB disease, prevention, treatment and sources of in...

Comparative whole-genome sequence analysis of Mycobacterium tuberculosis isolated from pulmonary tuberculosis and tuberculous lymphadenitis patients in Northwest Ethiopia 

Background: Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex (MTBC), is a chronic infectious disease with both pulmonary and extrapulmonary forms. This study set out to investigate and compare the genomic diversity and transmission dynamics of Mycobacterium tuberculosis (Mtb) iso...

Prevalence of Schistosoma haematobium and Intestinal Helminth Infections among Nigerian School Children 

Schistosomiasis and soil-transmitted helminthiases (STH) are two parasitic diseases mainly affecting school children. The purpose of this study was to estimate the current prevalence and infection intensity, in addition to the associations of these infections with age and sex, in children aged 4-17...

Diagnostic pathways of Chagas disease in Spain: a qualitative study 

Background: Due to the mobility of the population in recent years and the spread of Chagas disease (CD) to non-endemic regions, early diagnosis and treatment of CD has become increasingly relevant in non-endemic countries. In order for screening to be effective, health system accessibility must be ...

Evolución de las preocupaciones, percepciones y actitudes de la población española ante la pandemia de COVID-19 

[ES] En la pandemia de COVID-19, tanto el comportamiento individual como el colectivo son determinantes en el control de la propagación de la enfermedad, pero las restricciones adoptadas para atajar esta crisis de salud pública han afectado al bienestar físico y mental de la población. Conocer las ...

Assessing the use of acute malnutrition indicators for nutrition surveillance: Results from 682 283 child observations in 27 low- and middle-income countries 

Surveillance with anthropometric indicators is crucial to detect any deterioration in the nutritional status of a population as it provides information on trends to monitor progress and effectiveness of interventions and facilitates geographical and contextual situation analysis which informs prior...

Deletion patterns, genetic variability and protein structure of pfhrp2 and pfhrp3: implications for malaria rapid diagnostic test in Amhara region, Ethiopia 

Background: Although rapid diagnostic tests (RDTs) play a key role in malaria-control strategies, their efficacy has been threatened by deletion and genetic variability of the genes pfhrp2/3. This study aims to characterize the deletion, genetic patterns and diversity of these genes and their impli...

Knowledge, Attitudes, and Stigma: The Perceptions of Tuberculosis in Equatorial Guinea 

Tuberculosis remains one of the major causes of morbidity and mortality in Equatorial Guinea, with an estimated incidence of 280 per 100,000 inhabitants, an estimated mortality rate of 96 per 100,000 inhabitants, and a treatment non-adherence rate of 21.4%. This study aimed to identify the factors ...

Age differences in knowledge, attitudes and preventive practices during the COVID-19 pandemic in Spain 

This study aims at describing the evolution of Spanish population preventive practices during the COVID-19 pandemic of the between January and June 2021, and differences by age group. Data was drawn from the COSMO-Spain online survey, rounds (R) 4, 5 and 6. Multiple linear regression models with pr...

COVID-19 vaccine hesitancy in Spain and associated factors 

Introduction: The present study explores the reasons of those who have not been vaccinated in the later stage of the vaccine rollout in Spain and its associated determinants. Methods: Cluster and logistic regression analyses were used to assess differences in claimed reasons for vaccine hesitancy i...

Identification and Distribution of Human-Biting Ticks in Northwestern Spain 

Ticks transmit a wide diversity of pathogens to a great variety of hosts, including humans. We conducted a tick surveillance study in northwestern Spain between 2014 and 2019. Ticks were removed from people and identified. Tick numbers, species, development stages, the timeline, seasonal and geogra...