Envíos recientes

Alicante-Winter Immunology Symposium in Health (A-Wish) and the Boulle-SEI awards: A collaboration between the Spanish Society for immunology, the University of Alicante and the Jean Boulle Group to honor the Balmis Expedition 

The main objective of this annual symposium is to promote the development and advancement of the study of immunology, infectious diseases and vaccinology, as life and health sciences, as well as to disseminate the development of novel approaches in diagnosis and therapeutics of diseases that involv...

Brote de endocarditis por M. chimaera en Barcelona 

Comunicación presentada en el VI Congreso de la Sociedad Española de Infecciones Cardiovasculares (SEICAV) celebrado en Barcelona en septiembre de 2017.

Tyrosine kinase inhibition: the new front in HIV cure efforts 

Background: The HIV-1 latent reservoir persists largely through the natural ability of memory T cells to homeostatically proliferate in response to gc-cytokines IL-7 and IL-15. In addition, HIV-1 also infects cells of the myeloid lineage, a cell type that can penetrate protected tissues including t...

The Current Molecular Epidemiological Scenario of Cryptosporidium, Giardia and Blastocystis in Spain. Implication for Public Health 

The enteric protozoan parasites Cryptosporidium spp. and Giardia duodenalis are major contributors to the burden of gastrointestinal diseases globally. Both pathogens primarily affect children living in resource-poor settings with limited or no access to clean water and sanitation facilities, but a...

A Bayesian network approach to study host and viral genetic correlates of HIV-1 disease progression 

HIV disease progression is very variable among infected patients. Using classical statistical methods based on a selected number of markers, Casado et al [1] identified a number of host and viral genetic correlates for the clinical definitions of HIV-1 disease progression: elite controllers, long t...

Modifications in host cell structure and functions mediated by Tat intracellular expression are greatly dependent on the second exon 

The human immunodeficiency virus type 1 (HIV-1) encodes the 110 amino acid-pleiotropic nuclear transcriptional activator Tat that is not only essential for efficient elongation of viral transcripts, but also regulates both cellular protein and gene expression. Tat encoding gene consists of two spli...

Molecular mechanisms involved in HIV latency and implications for HIV treatment and eradication 

The aim of this presentation is to review the molecular mechanisms necessary for the establishment of HIV-1 latency, their relationship with different cellular and anatomic reservoirs, as well as the current treatment strategies targeting viral persistence in latent reservoirs, their main limitatio...