Artículos, contribuciones a congresos, datos de investigación, libros, capítulos de libro, patentes, tesis y trabajos de investigación.

Sub-communities within this community

  • ISCIII [2322]

    Instituto de Salud Carlos III
  • CNIC [966]

    Centro Nacional de Investigaciones Cardiovasculares
  • CNIO [403]

    Centro Nacional de Investigaciones Oncológicas

Recent Submissions

A Rapid Screening Program for Histoplasmosis, Tuberculosis, and Cryptococcosis Reduces Mortality in HIV Patients from Guatemala. 

Opportunistic infections (OIs) and advanced HIV disease (AHD) contribute to HIV-related mortality. Here, we analyzed the situation of AHD and OIs in a cohort of newly diagnosed HIV patients from Guatemala. We included 2127 adult patients from 13 facilities across the country during 2017 to 2018. Pa...

Percepciones de gestores de salud y facilitadores de la estrategia Atención Integrada a las Enfermedades Prevalentes (AIEPI) en una zona del Noreste de Brasil y Perú 

[ES] El objetivo del estudio fue explorar las percepciones sobre la estrategia de Atención Integrada a las Enfermedades Prevalentes en la Infancia (AIEPI) de gestores de salud y facilitadores de la estrategia. Se realizó una investigación de tipo cualitativo mediante entrevistas semiestructuradas. ...

Composition and Nutritional Quality of the Diet in Spanish Households during the First Wave of the COVID-19 Pandemic. 

In Spain, the health crisis caused by the COVID-19 pandemic led to the declaration of a state of alarm in the whole country in 2020; in this context, a nationwide lockdown was implemented, potentially altering the dietary habits of the population. The aims of this study were to describe the diet an...

Molecular Characterisation of Cryptosporidium spp. in Mozambican Children Younger than 5 Years Enrolled in a Matched Case-Control Study on the Aetiology of Diarrhoeal Disease. 

Cryptosporidium is a leading cause of childhood diarrhoea and associated physical and cognitive impairment in low-resource settings. Cryptosporidium-positive faecal samples (n = 190) from children aged ≤ 5 years enrolled in the Global Enteric Multicenter Study (GEMS) in Mozambique detected by ELISA...

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers. 

The effect of risk-reducing salpingo-oophorectomy (RRSO) on breast cancer risk for BRCA1 and BRCA2 mutation carriers is uncertain. Retrospective analyses have suggested a protective effect but may be substantially biased. Prospective studies have had limited power, particularly for BRCA2 mutation c...

Leishmaniasis visceral subclínica en 123 inpiduos de un cantón de la provincia Caranavi-La Paz: study in 123 inpiduals 

[ES] En 1999, en el Hospital del Niño se registró un nuevo caso de Leishmaniasis visceral sobre un niño de dos años proveniente del cantón de Taipiplaya (Provincia Caranavi). Por este motivo se realiza en este cantón una evaluación transversal de la leishmaniasis visceral mediante pruebas serológic...

El buen gobierno de los servicios de salud de producción pública: ideas para avanzar 

[ES] El buen desempeño de servicios de salud de producción pública tiene importancia vital, más allá del sector salud. Se aborda su buen gobierno y gestión a partir del marco conceptual de los valores e ideas del buen gobierno y de la experiencia de países más ejemplares, como referente práctico de...

Demographic and health attributes of the Nahua, initial contact population of the Peruvian Amazon. 

[EN] We present the case of the Nahua population of Santa Rosa de Serjali, Peruvian Amazon's population, considered of initial contact. This population consists of human groups that for a long time decided to live in isolation, but lately have begun living a more sedentary lifestyle and in contact ...

Differential Diagnosis of Fungal Pneumonias vs. Tuberculosis in AIDS Patients by Using Two New Molecular Methods. 

Opportunistic fungal pneumonias (OFP) are the main cause of death in AIDS patients worldwide. Diagnosis of these infections is often late as tuberculosis (TB) is frequently the first suspicion. In addition, diagnostic tools have limitations and are unavailable in disadvantaged regions. To perform t...

Los temas de salud en la Unión Europea: su impacto en la sanidad española 

[ES] El texto revisa el impacto de la integración europea en el sector salud (salud pública y servicios sanitarios), estudiando instituciones, funcionamiento y competencias de la Unión Europea (UE), a partir de literatura, documentos y observaciones coyunturales. La UE no tiene competencias directa...

La industria farmacéutica y la sostenibilidad de los sistemas de salud en países desarrollados y América Latina 

[ES] La crisis económica y su impacto en las finanzas públicas en la mayoría de los países desarrollados, están originando políticas de contención del gasto en los servicios de salud. Las leyes actuales del medicamento exigen calidad, seguridad y eficacia de estos productos. Algunos países inclu...

Comentario del CEIPV a la actualización de las Guías Europeas de Prevención Vascular en la Práctica Clínica 

[ES] Presentamos la adaptación para España de la actualización de las Guías Europeas de Prevención Vascular. En esta actualización se hace mayor énfasis en el abordaje poblacional, especialmente en la promoción de la actividad física y de una dieta saludable mediante políticas alimentarias y ...

Análisis de un brote de meningitis viral en la provincia de Tucumán, Argentina 

[ES] Confirmar la existencia de un brote de meningitis viral en 1996 en la provincia de Tucumán, Argentina, y estudiar sus características epidemiológicas. Se analizó información obtenida del Sistema Nacional de Vigilancia Epidemiológica (SINAVE) del Ministerio de Salud de Argentina para el período...

Intimate partner violence against Women during the COVID-19 lockdown in Spain. 

To analyze the temporal and geographical distribution of different indicators for the evolution of intimate partner violence against women (IPV) before, during and after the COVID-19 induced lockdown between March and June 2020 in Spain. Descriptive ecological study based on numbers of 016-calls, ...

Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis. 

HIV-1 infects CD4 T lymphocytes (CD4TL) through binding the chemokine receptors CCR5 or CXCR4. CXCR4-using viruses are considered more pathogenic, linked to accelerated depletion of CD4TL and progression to AIDS. However, counterexamples to this paradigm are common, suggesting heterogeneity in the ...

Correlation between biomarkers of pain in saliva and PAINAD Scale in elderly people with cognitive impairment and inability to communicate. 

The pain assessment in advanced dementia (PAINAD) appears to be a clinically useful tool. However, the salivary determination of tumor necrosis factor receptor type II (sTNF-RII) and secretory IgA (sIgA) as pain biomarkers is still incipient. The aim was to correlate the PAINAD score with sTNF-RII ...

RGB-Marking to Identify Patterns of Selection and Neutral Evolution in Human Osteosarcoma Models. 

Osteosarcoma (OS) is a highly aggressive tumor characterized by malignant cells producing pathologic bone; the disease presents a natural tendency to metastasize. Genetic studies indicate that the OS genome is extremely complex, presenting signs of macro-evolution, and linear and branched patterns ...

Tumor stem cells fuse with monocytes to form highly invasive tumor-hybrid cells. 

The 'cancer cell fusion' theory is controversial due to the lack of methods available to identify hybrid cells and to follow the phenomenon in patients. However, it seems to be one of the best explanations for both the origin and metastasis of primary tumors. Herein, we co-cultured lung cancer stem...

Empagliflozin improves post-infarction cardiac remodeling through GTP enzyme cyclohydrolase 1 and irrespective of diabetes status. 

Sodium-glucose co-transporter-2 inhibitors (SGLT2i) have shown to prevent heart failure progression, although the mechanisms remain poorly understood. Here we evaluated the effect of empagliflozin (EMPA, SGLT2i) in cardiac remodeling after myocardial infarction, the interplay with diabetes status a...

Decrement Evoked Potential Mapping to Guide Ventricular Tachycardia Ablation: Elucidating the Functional Substrate. 

Empirical approaches to targeting the ventricular tachycardia (VT) substrate include mapping of late potentials, local abnormal electrogram, pace-mapping and homogenisation of the abnormal signals. These approaches do not try to differentiate between the passive or active role of local signals as t...