Browsing Investigación by Institution "CNIO"

Now showing items 1-20 of 441

2022-01-13

A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo

journal article

Hanke, Leo; Das, Hrishikesh; Sheward, Daniel J.; et al.
2019-02-04

A cancer-associated point mutation disables the steric gate of human PrimPol

journal article

Díaz-Talavera, Alberto; Calvo, Patricia A; Gonzalez-Acosta, Daniel CNIO; et al.
2021-02-17

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.

journal article

Coignard, Juliette; Lush, Michael; Beesley, Jonathan; et al.
2019-07-16

A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells

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Olbrich, Teresa; Vega-Sendino, Maria; Murga, Matilde CNIO; et al.
2019-05

A common SNP in the UNG gene decreases ovarian cancer risk in BRCA2 mutation carriers

journal article

Baquero, Juan Miguel; Benítez-Buelga, Carlos; Fernández, Victoria; et al.
2020-04-14

A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.

journal article

Neupane, Ritam; Pisareva, Vera P; Rodriguez, Carlos F; et al.
2020-03-27

A comprehensive analysis of candidate genes in familial pancreatic cancer families reveals a high frequency of potentially pathogenic germline variants.

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Earl, Julie; Galindo-Pumariño, Cristina; Encinas, Jessica; et al.
2022-03-08

A faecal microbiota signature with high specificity for pancreatic cancer.

journal article

Kartal, Ece; Schmidt, Thomas S B; Wirbel, Jakob; et al.
2016-12

A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance

journal article

Martínez, Paula; Gómez-López, Gonzalo; Pisano, David G; et al.
2016-04-21

A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors

journal article

Ruiz, Sergio; Mayor-Ruiz, Cristina CNIO; Lafarga, Vanesa CNIO; et al.
2020-11-01

A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.

journal article

Pattwell, Siobhan S; Arora, Sonali; Cimino, Patrick J; et al.
2022-09-28

A Large Case-Control Study Performed in Spanish Population Suggests That RECQL5 Is the Only RECQ Helicase Involved in Breast Cancer Susceptibility.

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Marchena-Perea, Erik Michel; Salazar-Hidalgo, Milton Eduardo; Gómez-Sanz, Alicia; et al.
2017-06-30

A molecular hypothesis to explain direct and inverse co-morbidities between Alzheimer's Disease, Glioblastoma and Lung cancer

journal article

Sánchez-Valle, Jon; Tejero, Héctor; Ibáñez, Kristina; et al.
2019-08-22

A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions

journal article

Moll, Herwig P; Mohrherr, Julian; Blaas, Leander; et al.
2015

A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families

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Calvete O CNIO; Martinez, Paula CNIO; Garcia-Pavia, Pablo CNIC; et al.
2020-11-01

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.

journal article

Escala-Garcia, Maria; Abraham, Jean; Andrulis, Irene L; et al.
2017-03-09

A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer

journal article

Forés, Marta; Simón-Carrasco, Lucía; Ajuria, Leiore; et al.
2020-07-02

A Novel Approach for the Identification of Pharmacogenetic Variants in MT-RNR1 through Next-Generation Sequencing Off-Target Data.

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Lanillos, Javier; Santos, María; Carcajona, Marta; et al.
2017-05-26

A novel community driven software for functional enrichment analysis of extracellular vesicles data

journal article

Pathan, Mohashin; Keerthikumar, Shivakumar; Chisanga, David; et al.
2019-02

A novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia

journal article

Onecha, Esther; Linares, Maria; Rapado, Inmaculada; et al.