Publication: Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination
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2023-02
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Aznar, Esteban
Casas Flecha, Inmaculada ISCIII 
González Praetorius, Alejandro
Ruano Ramos, María José
Pozo Sanchez, Francisco ISCIII
Sierra Moros, María José
García Rivera, María Victoria
Sánchez Sánchez, Azucena
García Villacieros, Elena
Saravia, Gabriela CNIC
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European Centre for Disease Prevention and Control (ECDC)
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Abstract
In autumn 2022, the Spanish Influenza National Reference Laboratory (NRL) confirmed the detection of influenza A(H5N1) in samples from two asymptomatic workers linked to an outbreak in a poultry farm in Spain. Nasopharyngeal swabs were taken according to a national screening protocol for exposed workers. Absence of symptoms, low viral load and negative serology in both workers suggested environmental contamination. These findings motivated an update of the early detection strategy specifying timing and sampling conditions in asymptomatic exposed persons.
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Euro Surveill. 2023 Feb;28(8):2300107.