Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/16087
Title
Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022
Author(s)
Linkevicius, Marius | Bonnin, Rémy A | Alm, Erik | Svartström, Olov | Apfalter, Petra | Hartl, Rainer | Hasman, Henrik | Roer, Louise | Räisänen, Kati | Dortet, Laurent | Pfennigwerth, Niels | Hans, Jörg B | Tóth, Ákos | Buzgó, Lilla | Cormican, Martin | Delappe, Niall | Monaco, Monica | Giufrè, Maria | Hendrickx, Antoni Pa | Samuelsen, Ørjan | Pöntinen, Anna K | Caniça, Manuela | Manageiro, Vera | Oteo-Iglesias, Jesus ISCIII | Perez-Vazquez, Maria ISCIII | Westmo, Karin | Mäkitalo, Barbro | Palm, Daniel | Monnet, Dominique L | Kohlenberg, Anke
Date issued
2023-05
Citation
Euro Surveill. 2023 May;28(19):2300209.
Language
Inglés
Document type
journal article
Abstract
Whole genome sequencing data of 874 Escherichia coli isolates carrying bla NDM-5 from 13 European Union/European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were predicted to be multidrug-resistant. Further spread of E. coli carrying bla NDM-5 would leave limited treatment options for serious E. coli infections.
Subject
Carbapenem-resistant Enterobacterales | Escherichia coli | NDM-5 | Carbapenemase | Cross-border import | Surveillance | Whole genome sequencing
MESH
Escherichia coli | Escherichia coli Infections | Humans | beta-Lactamases | Drug Resistance, Multiple, Bacterial | European Union | Microbial Sensitivity Tests | Europe
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