Please use this identifier to cite or link to this item:http://hdl.handle.net/20.500.12105/15584
Economic Burden And Health-Related Quality Of Life Of Patients With Cystic Fibrosis In Bulgaria
Folia Med (Plovdiv). 2015 Jan-Mar;57(1):56-64.
Objective: The aim of this study was to determine the economic burden from a societal perspective and health-related quality of life (HRQOL) of patients with cystic fibrosis (CF) in Bulgaria. Materials and methods: We conducted a cross-sectional study of 33 patients with CF and 17 caregivers from Bulgaria. Data on socio-demographic characteristics, health resource utilisation, informal care, labor productivity losses and HRQOL were collected from questionnaires completed by patients or their caregivers. HRQOL was evaluated with the EuroQol 5-domain (EQ-5D-3L) questionnaire. Results: Median annual costs of CF in Bulgaria were € 24 152 per patient in 2012 as a reference year. Median annual costs for children were found to be significantly higher than those for adults - € 31 945 vs. € 15 714 (p = 0.012). This outcome came from statistically significant differences in costs for main informal carer (p < 0.001) and costs for other informal carers (p = 0.022). As a single cost item, drugs had the biggest monetary impact. Median annual drug costs were € 13 059. Bulgarian CF patients showed low HRQOL results - 50 median VAS score and 0.592 median health utilities. A quarter of patients even rated their health state as worse than death. Conclusion: CF patients from Eastern Europe remain a vulnerable population with risk factors for worse health outcomes. Our study provided a state-of-the art analysis that facilitates the elaboration, adoption and application of targeted public health policies to tackle CF-related problems at national and European level.
Cystic fibrosis | Health-related quality of life | Costs and cost analysis | Economic burden | Bulgaria
Quality of Life | Adolescent | Adult | Bulgaria | Child | Cost of Illness | Cross-Sectional Studies | Cystic Fibrosis | Drug Costs | Female | Humans | Male
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