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dc.contributor.authorAapola, Ulla
dc.contributor.authorNättinen, Janika
dc.contributor.authorSuurkuukka, Ilona
dc.contributor.authorTuomilehto, Jaakko 
dc.contributor.authorKeinänen-Kiukaanniemi, Sirkka
dc.contributor.authorSaramies, Jouko
dc.contributor.authorUusitalo, Hannu
dc.date.accessioned2022-05-26T11:29:31Z
dc.date.available2022-05-26T11:29:31Z
dc.date.issued2022-03-24
dc.identifier.citationActa Ophthalmol. 2022 Mar 24.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/14550
dc.description.abstractPurpose: The aim of this study was to describe the clinical ocular surface characteristics in a population-based sample of Finnish elderly people. Methods: This cross-sectional study included 601 subjects (335 females, 266 males) born between the years 1933-1956 and living in Savitaipale, Finland. Ocular surface health was evaluated using a comprehensive set of diagnostic tests. Previous dry eye (DE) diagnosis and history of drug treatment of DE were also recorded. Differences between sexes were estimated with Wilcoxon rank sum test and Fisher's exact test. Results: Overall, 10% and 33% of people displayed signs of DE and ocular surface disease (OSD), respectively, and 30% had been previously diagnosed with DE and 36% used some form of drugs for DE. Men displayed more severe signs of meibomian gland dysfunction, blepharitis and conjunctival redness (p < 0.001), while women had higher scores in corneal staining (p = 0.005) and OSD Index (p < 0.001). Conclusion: Signs of OSD and DE are common among the Finnish elderly population. However, the diagnosis is affected by the diagnostic criteria used and significant differences exist between sexes. Although women were more frequently diagnosed with DE and OSD and experienced more ocular surface irritation, men had more often lid and meibomian gland-related issues. The current diagnostic criteria of DE pose a risk of misclassifying men, who commonly display less severe symptoms in comparison with women yet exhibit more severe clinical signs associated especially with the lid margin.es_ES
dc.description.sponsorshipThis work was supported by Business Finland, Elsemay Bjorn Fund, Glaukooma Tukisäätiö Lux, Pirkanmaa Regional Fund and Competitive State Research Financing of the Expert Responsibility area of Helsinki University Hospital. The funding sources were not involved in study design, data collection, analysis and interpretation, decision to publish or preparation of this article.es_ES
dc.language.isoenges_ES
dc.publisherWiley es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectDry eye diseasees_ES
dc.subjectEpidemiologyes_ES
dc.subjectOcular surface diseasees_ES
dc.subjectPrevalencees_ES
dc.titleOcular surface health of the Finnish elderly populationes_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID35322930es_ES
dc.identifier.doi10.1111/aos.15130es_ES
dc.contributor.funderBusiness Finlandes_ES
dc.contributor.funderElsemay Bjorn Fundes_ES
dc.contributor.funderGlaukooma Tukisäätiö Luxes_ES
dc.contributor.funderPirkanmaa Regional Fundes_ES
dc.contributor.funderHelsinki University Hospitales_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1755-3768es_ES
dc.relation.publisherversionhttps://doi.org/10.1111/aos.15130es_ES
dc.identifier.journalActa ophthalmologicaes_ES
dc.repisalud.centroISCIII::Escuela Nacional de Sanidades_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Atribución 4.0 Internacional