Mostrar el registro sencillo del ítem

dc.contributor.authorPadilla-Ruiz, María
dc.contributor.authorMorales-Suárez-Varela, María
dc.contributor.authorRivas-Ruiz, Francisco
dc.contributor.authorAlcaide, Julia
dc.contributor.authorVarela-Moreno, Esperanza
dc.contributor.authorZarcos-Pedrinaci, Irene
dc.contributor.authorTéllez, Teresa
dc.contributor.authorFernandez de Larrea-Baz, Nerea 
dc.contributor.authorBaré, Marisa
dc.contributor.authorBilbao, Amaia
dc.contributor.authorSarasqueta, Cristina
dc.contributor.authorAguirre-Larracoechea, Urko
dc.contributor.authorQuintana, José María
dc.contributor.authorRedondo, Maximino
dc.contributor.authorCARESS-CCR Study Group
dc.date.accessioned2022-05-24T08:17:16Z
dc.date.available2022-05-24T08:17:16Z
dc.date.issued2022-03-18
dc.identifier.citationInt J Environ Res Public Health. 2022 Mar 18;19(6):3626.es_ES
dc.identifier.otherhttp://hdl.handle.net/10668/21047
dc.identifier.urihttp://hdl.handle.net/20.500.12105/14474
dc.description.abstractColorectal cancer affects men and women alike. Sometimes, due to clinical-pathological factors, the absence of symptoms or the failure to conduct screening tests, its diagnosis may be delayed. However, it has not been conclusively shown that such a delay, especially when attributable to the health system, affects survival. The aim of the present study is to evaluate the overall survival rate of patients with a delayed diagnosis of colorectal cancer. This observational, prospective, multicenter study was conducted at 22 public hospitals located in nine Spanish provinces. For this analysis, 1688 patients with complete information in essential variables were included. The association between diagnostic delay and overall survival at five years, stratified according to tumor location, was estimated by the Kaplan-Meier method. Hazard ratios for this association were estimated using multivariable Cox regression models. The diagnostic delay ≥ 30 days was presented in 944 patients. The presence of a diagnostic delay of more than 30 days was not associated with a worse prognosis, contrary to a delay of less than 30 days (HR: 0.76, 0.64-0.90). In the multivariate analysis, a short delay maintained its predictive value (HR: 0.80, 0.66-0.98) regardless of age, BMI, Charlson index or TNM stage. A diagnostic delay of less than 30 days is an independent factor for short survival in patients with CRC. This association may arise because the clinical management of tumors with severe clinical characteristics and with a poorer prognosis are generally conducted more quickly.es_ES
dc.description.sponsorshipThis study was supported by public grants from Instituto de Salud Carlos III (PI09/90397, PS09/00314, PS09/00746, PI09/90453, PI09/00910, PI09/90460, PI09/90490, PI13/01692, PI13/00013, PI18/01181, PI18/01589, PS0900805 & PI0900441) and was co-funded by the European Regional Development Fund.es_ES
dc.language.isoenges_ES
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectColorectal neoplasmses_ES
dc.subjectDelayed diagnosises_ES
dc.subjectMortalityes_ES
dc.subjectProspective cohort studyes_ES
dc.subjectSurvivales_ES
dc.titleInfluence of Diagnostic Delay on Survival Rates for Patients with Colorectal Canceres_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID35329320es_ES
dc.format.volume19es_ES
dc.format.number6es_ES
dc.format.page3626es_ES
dc.identifier.doi10.3390/ijerph19063626es_ES
dc.contributor.funderInstituto de Salud Carlos III es_ES
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1660-4601es_ES
dc.relation.publisherversionhttps://doi.org/10.3390/ijerph19063626es_ES
dc.identifier.journalInternational Journal of Environmental Research and Public Healthes_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90397es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PS09/00314es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PS09/00746es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90453es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/00910es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90460es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90490es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI13/01692es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI13/00013es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI18/01181es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI18/01589es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PS0900805es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI0900441es_ES


Ficheros en el ítem

Acceso Abierto
Thumbnail

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

Atribución 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Atribución 4.0 Internacional