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dc.contributor.author | Saez-Nieto, Juan Antonio | |
dc.contributor.author | Carrasco, Gema | |
dc.contributor.author | Pino-Rosa, Silvia del | |
dc.contributor.author | Medina-Pascual, Maria Jose | |
dc.contributor.author | Garrido, Noelia | |
dc.contributor.author | Villalon-Panzano, Pilar | |
dc.contributor.author | Valdezate, Sylvia | |
dc.date.accessioned | 2022-05-09T11:52:13Z | |
dc.date.available | 2022-05-09T11:52:13Z | |
dc.date.issued | 2021-12 | |
dc.identifier.citation | New Microbes New Infect. 2021 Dec 13;44:100946. | es_ES |
dc.identifier.issn | 2052-2975 | es_ES |
dc.identifier.uri | http://hdl.handle.net/20.500.12105/14342 | |
dc.description.abstract | Two hundred and eighty-six isolates from human clinical samples were identified between 1996 and 2019 as belonging to 8 families, 19 genera and 88 species of Actinobacteria. The most identified genera were Streptomyces (182 strains from 45 species), Actinomadura (29 strains, 5 species), Nocardiopsis (21 strains, 6 species) and Dietzia (18 strains, 5 species). The rest of the identified genera (15) contained 27 species with 36 isolates. Of the species studied, only 13/88 had been documented previously as isolates from clinical samples, and in some cases, as true pathogens. In this sense, a literature review of the species found in infections or in clinical samples without clear involvement in pathology has been carried out. Finally, the susceptibility to 8 antimicrobial agents has been studied. Streptomyces showed high resistance (80.8%) against cefotaxime and cotrimoxazole (55.5%), and no isolate resistance to amikacin and linezolid have been found. Lower percentages of resistance have been found in other genera, except in Dietzia (100% against cotrimoxazole and 44.4% against erythromycin). The greatest resistance in these genera was to cotrimoxazole (29.8) and erythromycin (27,9%), and no resistance to linezolid has been found in these genera. In Microbispora, Nonomuraea and Umezawaea, no resistant isolates have been found against any antibiotic studied. Only 3/104 isolates were resistant to amikacin in Amycolatopsis, Crossiella, and Micromonosopora. One isolate of Amycolatopsis was resistant to imipenem. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.type.hasVersion | VoR | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Actimomadura | es_ES |
dc.subject | Actinobacteria | es_ES |
dc.subject | Streptomyces | es_ES |
dc.subject | Antimicrobial susceptibility | es_ES |
dc.subject | Human clinical samples | es_ES |
dc.title | Identification and antimicrobial susceptibility of Streptomyces and other unusual Actinobacteria clinical isolates in Spain | es_ES |
dc.type | journal article | es_ES |
dc.rights.license | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.identifier.pubmedID | 34917388 | es_ES |
dc.format.volume | 44 | es_ES |
dc.format.page | 100946 | es_ES |
dc.identifier.doi | 10.1016/j.nmni.2021.100946 | es_ES |
dc.description.peerreviewed | Sí | es_ES |
dc.relation.publisherversion | https://doi.org/10.1016/j.nmni.2021.100946 | es_ES |
dc.identifier.journal | New Microbes and New Infections | es_ES |
dc.repisalud.centro | ISCIII::Centro Nacional de Microbiología | es_ES |
dc.repisalud.institucion | ISCIII | es_ES |
dc.rights.accessRights | open access | es_ES |