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dc.contributor.authorSantonen, Tiina
dc.contributor.authorPorras, Simo P
dc.contributor.authorBocca, Beatrice
dc.contributor.authorBousoumah, Radia
dc.contributor.authorDuca, Radu Corneliu
dc.contributor.authorGalea, Karen S
dc.contributor.authorGodderis, Lode
dc.contributor.authorGöen, Thomas
dc.contributor.authorHardy, Emilie
dc.contributor.authorIavicoli, Ivo
dc.contributor.authorJanasik, Beata
dc.contributor.authorJones, Kate
dc.contributor.authorLeese, Elizabeth
dc.contributor.authorLeso, Veruscka
dc.contributor.authorLouro, Henriqueta
dc.contributor.authorMajery, Nicole
dc.contributor.authorNdaw, Sophie
dc.contributor.authorPinhal, Hermínia
dc.contributor.authorRuggieri, Flavia
dc.contributor.authorSilva, Maria J
dc.contributor.authorvan Nieuwenhuyse, An
dc.contributor.authorVerdonck, Jelle
dc.contributor.authorViegas, Susana
dc.contributor.authorWasowicz, Wojciech
dc.contributor.authorSepai, Ovnair
dc.contributor.authorScheepers, Paul T J
dc.contributor.authorCastaño, Argelia 
dc.contributor.authorEsteban-Lopez, Marta 
dc.contributor.authorHBM4EU chromates study team
dc.date.accessioned2022-04-27T10:47:25Z
dc.date.available2022-04-27T10:47:25Z
dc.date.issued2022-03
dc.identifier.citationEnviron Res. 2022 Mar;204(Pt A):111984.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/14200
dc.description.abstractExposure to hexavalent chromium [Cr(VI)] may occur in several occupational activities, e.g., welding, Cr(VI) electroplating and other surface treatment processes. The aim of this study was to provide EU relevant data on occupational Cr(VI) exposure to support the regulatory risk assessment and decision-making. In addition, the capability and validity of different biomarkers for the assessment of Cr(VI) exposure were evaluated. The study involved nine European countries and involved 399 workers in different industry sectors with exposures to Cr(VI) such as welding, bath plating, applying or removing paint and other tasks. We also studied 203 controls to establish a background in workers with no direct exposure to Cr(VI). We applied a cross-sectional study design and used chromium in urine as the primary biomonitoring method for Cr(VI) exposure. Additionally, we studied the use of red blood cells (RBC) and exhaled breath condensate (EBC) for biomonitoring of exposure to Cr(VI). Personal measurements were used to study exposure to inhalable and respirable Cr(VI) by personal air sampling. Dermal exposure was studied by taking hand wipe samples. The highest internal exposures were observed in the use of Cr(VI) in electrolytic bath plating. In stainless steel welding the internal Cr exposure was clearly lower when compared to plating activities. We observed a high correlation between chromium urinary levels and air Cr(VI) or dermal total Cr exposure. Urinary chromium showed its value as a first approach for the assessment of total, internal exposure. Correlations between urinary chromium and Cr(VI) in EBC and Cr in RBC were low, probably due to differences in kinetics and indicating that these biomonitoring approaches may not be interchangeable but rather complementary. This study showed that occupational biomonitoring studies can be conducted successfully by multi-national collaboration and provide relevant information to support policy actions aiming to reduce occupational exposure to chemicals.es_ES
dc.description.sponsorshipThis work has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No 733032 and received co-funding from the author's organizations and/or Ministries. Luxembourg entered the study at a later stage and thus financed the study at its own means.es_ES
dc.language.isoenges_ES
dc.publisherElsevier es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectBiomonitoringes_ES
dc.subjectElectroplatinges_ES
dc.subjectHexavalent chromiumes_ES
dc.subjectOccupational exposurees_ES
dc.subjectWeldinges_ES
dc.titleHBM4EU chromates study - Overall results and recommendations for the biomonitoring of occupational exposure to hexavalent chromiumes_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID34492275es_ES
dc.format.volume204es_ES
dc.format.numberPt4es_ES
dc.format.page111984es_ES
dc.identifier.doi10.1016/j.envres.2021.111984es_ES
dc.contributor.funderUnión Europea. Comisión Europea. H2020 es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1096-0953es_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.envres.2021.111984es_ES
dc.identifier.journalEnvironmental Researches_ES
dc.repisalud.centroISCIII::Centro Nacional de Sanidad Ambientales_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/733032/EUes_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Atribución 4.0 Internacional