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dc.contributor.authorGonzález, Nerea
dc.contributor.authorLoroño, Ane
dc.contributor.authorAguirre, Urko
dc.contributor.authorLázaro, Santiago
dc.contributor.authorBaré, Marisa
dc.contributor.authorRedondo, Maximino
dc.contributor.authorBriones, Eduardo
dc.contributor.authorSarasqueta, Cristina
dc.contributor.authorBilbao, Amaia
dc.contributor.authorFernandez de Larrea-Baz, Nerea 
dc.contributor.authorQuintana, José María
dc.contributor.authorREDISSEC-CARESS/CCR Group
dc.date.accessioned2022-04-26T11:39:00Z
dc.date.available2022-04-26T11:39:00Z
dc.date.issued2021-08-26
dc.identifier.citationWorld J Surg Oncol. 2021;19(1):252.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/14185
dc.description.abstractBackground: The aim of this study was to identify predictors of mortality in elderly patients undergoing colorectal cancer surgery and to develop a risk score. Methods: This was an observational prospective cohort study. Individuals over 80 years diagnosed with colorectal cancer and treated surgically were recruited in 18 hospitals in the Spanish National Health Service, between June 2010 and December 2012, and were followed up 1, 2, 3, and 5 years after surgery. Sociodemographic and clinical data were collected. The primary outcomes were mortality at 2 and between 2 and 5 years after the index admission. Results: The predictors of mortality 2 years after surgery were haemoglobin ≤ 10 g/dl and colon locations (HR 1.02; CI 0.51-2.02), ASA class of IV (HR 3.55; CI 1.91-6.58), residual tumour classification of R2 (HR 7.82; CI 3.11-19.62), TNM stage of III (HR 2.14; CI 1.23-3.72) or IV (HR 3.21; CI 1.47-7), LODDS of more than - 0.53 (HR 3.08; CI 1.62-5.86)) and complications during admission (HR 1.73; CI 1.07-2.80). Between 2 and 5 years of follow-up, the predictors were no tests performed within the first year of follow-up (HR 2.58; CI 1.21-5.46), any complication due to the treatment within the 2 years of follow-up (HR 2.47; CI 1.27-4.81), being between 85 and 89 and not having radiotherapy within the second year of follow-up (HR 1.60; CI 1.01-2.55), no colostomy closure within the 2 years of follow-up (HR 4.93; CI 1.48-16.41), medical complications (HR 1.61; CI 1.06-2.44), tumour recurrence within the 2 years of follow-up period (HR 3.19; CI 1.96-5.18), and readmissions at 1 or 2 years of follow-up after surgery (HR 1.44; CI 0.86-2.41). Conclusion: We have identified variables that, in our sample, predict mortality 2 and between 2 and 5 years after surgery for colorectal cancer older patients. We have also created risks scores, which could support the decision-making process.es_ES
dc.description.sponsorshipThis work was supported in part by grants from the Spanish Health Research Fund (PS09/00314, PS09/00910, PS09/00746, PS09/00805, PI09/90460, PI09/90490, PI09/90397, PI09/90453, PI09/90441; PI13/01692; PI13/00013); Department of Health of the Basque Country (2010111098); KRONIKGUNE, Institute for Health Services Research (KRONIK 11/006); and the European Regional Development Fund. These institutions had no further role in study design; in the collection, analysis, or interpretation of data; in the writing of the manuscript; or in the decision to submit the paper for publication.es_ES
dc.language.isoenges_ES
dc.publisherBioMed Central (BMC) es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectColorectal canceres_ES
dc.subjectElderlyes_ES
dc.subjectMortalityes_ES
dc.subjectOutcomees_ES
dc.subjectRisk scorees_ES
dc.subjectSurgeryes_ES
dc.subject.meshColorectal Neoplasms es_ES
dc.subject.meshState Medicine es_ES
dc.subject.meshAged es_ES
dc.subject.meshHumans es_ES
dc.subject.meshNeoplasm Recurrence, Locales_ES
dc.subject.meshPrognosis es_ES
dc.subject.meshProspective Studies es_ES
dc.subject.meshRisk Factors es_ES
dc.titleRisk scores to predict mortality 2 and 5 years after surgery for colorectal cancer in elderly patientses_ES
dc.typejournal articlees_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.identifier.pubmedID34446044es_ES
dc.format.volume19es_ES
dc.format.number1es_ES
dc.format.page252es_ES
dc.identifier.doi10.1186/s12957-021-02356-6es_ES
dc.contributor.funderBasque Government (España) es_ES
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) es_ES
dc.contributor.funderInstituto de Salud Carlos III es_ES
dc.contributor.funderKronikgunees_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1477-7819es_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.sleep.2016.04.019es_ES
dc.identifier.journalWorld Journal of Surgical Oncologyes_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PS09/00314es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PS09/00910es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PS09/00746es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PS09/00805es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90460es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90490es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90397es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90453es_ES
dc.relation.projectFISinfo:eu-repo/grantAgreement/ES/PI09/90441es_ES
dc.relation.projectFISinfo:fis/Instituto de Salud Carlos III/null/null/Subprograma de proyectos de investigacion en salud (AES 2013) (2013)/PI13/01692es_ES
dc.relation.projectFISinfo:fis/Instituto de Salud Carlos III/null/null/Subprograma de proyectos de investigacion en salud (AES 2013) (2013)/PI13/00013es_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Attribution-NonCommercial-NoDerivatives 4.0 Internacional