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dc.contributor.authorGarcía-Velasco, Adelaida
dc.contributor.authorZacarías-Pons, Lluís
dc.contributor.authorTeixidor, Helena
dc.contributor.authorValeros, Marc
dc.contributor.authorLiñan, Raquel
dc.contributor.authorCarmona-Garcia, M Carmen
dc.contributor.authorPuigdemont, Montse
dc.contributor.authorCarbajal, Walter
dc.contributor.authorGuardeño, Raquel
dc.contributor.authorMalats, Nuria 
dc.contributor.authorDuell, Eric
dc.contributor.authorMarcos-Gragera, Rafael
dc.identifier.citationInt J Environ Res Public Health . 2020;17(24):9538.es_ES
dc.description.abstract(1) Background: We investigated the incidence and survival trends for pancreatic cancer (PC) over the last 25 years in the Girona region, Catalonia, Spain; (2) Methods: Data were extracted from the population-based Girona Cancer Registry. Incident PC cases during 1994-2015 were classified using the International Classification of Diseases for Oncology Third Edition (ICD-O-3). Incidence rates age-adjusted to the European standard population (ASRE) and world standard population (ASRW) were obtained. Trends were assessed using the estimated annual percentage of change (EAPC) of the ASRE13. Observed and relative survivals (RS) were estimated with the Kaplan-Meier and Pohar Perme methods, respectively; (3) Results: We identified 1602 PC incident cases. According to histology, 44.4% of cases were exocrine PC, 4.1% neuroendocrine, and 51.1% malignant-non-specified. The crude incidence rate (CR) for PC was 11.43 cases-per-100,000 inhabitants/year. A significant increase of incidence with age and over the study period was observed. PC overall 5-year RS was 7.05% (95% confidence interval (CI) 5.63; 8.84). Longer overall survival was observed in patients with neuroendocrine tumours (5-year RS 61.45%; 95% CI 47.47; 79.55). Trends in 5-year RS for the whole cohort rose from 3.27% (95% CI 1.69-6.35) in 1994-1998 to 13.1% (95% CI 9.98; 17.2) in 2010-2015; (4) Conclusions: Incidence rates of PC in Girona have increased in the last two decades. There is a moderate but encouraging increase in survival thorough the study period. These results can be used as baseline for future research.es_ES
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI) es_ES
dc.subject.meshAdolescent es_ES
dc.subject.meshAdult es_ES
dc.subject.meshAged es_ES
dc.subject.meshFemale es_ES
dc.subject.meshHumans es_ES
dc.subject.meshIncidence es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshPancreatic Neoplasms es_ES
dc.subject.meshPopulation Surveillance es_ES
dc.subject.meshRegistries es_ES
dc.subject.meshSpain es_ES
dc.subject.meshSurvival Rate es_ES
dc.subject.meshYoung Adult es_ES
dc.titleIncidence and Survival Trends of Pancreatic Cancer in Girona: Impact of the Change in Patient Care in the Last 25 Years.es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.identifier.journalInternational journal of environmental research and public healthes_ES
dc.repisalud.orgCNIOCNIO::Grupos de investigación::Grupo de Epidemiología Genética y Moleculares_ES
dc.rights.accessRightsopen accesses_ES

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