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dc.contributor.authorSalvador, Fernando
dc.contributor.authorLobo, Beatriz
dc.contributor.authorGoterris, Lidia
dc.contributor.authorAlonso-Cotoner, Carmen
dc.contributor.authorSantos, Javier
dc.contributor.authorSulleiro, Elena
dc.contributor.authorBailo-Barroso, Begoña 
dc.contributor.authorCarmena, David 
dc.contributor.authorSánchez-Montalvá, Adrián
dc.contributor.authorBosch-Nicolau, Pau
dc.contributor.authorEspinosa-Pereiro, Juan
dc.contributor.authorFuentes, Isabel 
dc.contributor.authorMolina, Israel
dc.date.accessioned2021-05-09T14:34:47Z
dc.date.available2021-05-09T14:34:47Z
dc.date.issued2021-04-19
dc.identifier.citationBiology (Basel) . 2021 Apr 19;10(4):340.es_ES
dc.identifier.issn2079-7737es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/12913
dc.description.abstractThe aim of the present study is to describe the occurrence of Blastocystis sp. detection among asymptomatic subjects and patients with irritable bowel syndrome in order to evaluate the potential association between irritable bowel syndrome and the parasitic infection. Cross-sectional study where adult patients with irritable bowel syndrome diagnosed according to Rome IV criteria were included. A control group was formed by asymptomatic subjects older than 18 years. Exclusion criteria were: immunosuppressive condition or having received any drug with demonstrated activity against Blastocystis sp. within the last 6 months before study inclusion. Epidemiological and clinical information was collected from all included participants. Two stool samples were obtained from all participants: one sample for microscopic examination and one sample for Blastocystis sp. PCR detection. Blastocystis sp. infection was defined by the positivity of any of the diagnostic techniques. Seventy-two participants were included (36 asymptomatic subjects and 36 patients with irritable bowel syndrome). Thirty-five (48.6%) were men, and median age of participants was 34 (IQR 29-49) years. The overall rate of Blastocystis sp. carriage was 27.8% (20/72). The prevalence assessed through microscopic examination was 22.2% (16/72), while the prevalence measured by PCR was 15.3% (11/72). When comparing the presence of Blastocystis sp. between asymptomatic subjects and IBS patients, we did not find any statistically significant difference (36.1% vs. 19.4% respectively, p = 0.114). regarding the occurrence of Blastocystis sp., no differences were found between asymptomatic participants and patients with irritable bowel disease irrespective of the diagnostic technique performed.es_ES
dc.description.sponsorshipThis study was supported by the ISCIII-Collaborative Research Network on Tropical Diseases (RICET) and the European Regional Development Fund (ERDF): RD16/0027/0003 and RD16CIII/0003/0004.es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectBlastocystis sp.es_ES
dc.subjectIrritable Bowel Syndromees_ES
dc.subjectPathogenesises_ES
dc.titleBlastocystis sp. Carriage and Irritable Bowel Syndrome: Is the Association Already Established?es_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID33921803es_ES
dc.format.volume10es_ES
dc.format.number4es_ES
dc.identifier.doi10.3390/biology10040340es_ES
dc.contributor.funderRed de Investigación Cooperativa en Enfermedades Tropicales (España)es_ES
dc.contributor.funderEuropean Regional Development Fund (ERDF/FEDER)es_ES
dc.description.peerreviewedes_ES
dc.relation.publisherversionhttps://doi.org/10.3390/biology10040340es_ES
dc.identifier.journalBiologyes_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/RD16/0027/0003es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/RD16CIII/0003/0004es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Atribución 4.0 Internacional
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