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dc.contributor.authorFerreira, Eduardo de Castro
dc.contributor.authorCruz, Israel 
dc.contributor.authorCañavate, Carmen 
dc.contributor.authorde Melo, Lutiana Amaral
dc.contributor.authorPereira, Agnes Antônia Sampaio
dc.contributor.authorMadeira, Filipe A M
dc.contributor.authorValério, Sofia Alves Nogueira
dc.contributor.authorCunha, Heitor Morais
dc.contributor.authorPaglia, Adriano Pereira
dc.contributor.authorGontijo, Célia Maria Ferreira
dc.identifier.citationBMC Vet Res . 2015 Mar 20;11:71.es_ES
dc.description.abstractIn Brazil Leishmania braziliensis and L. infantum are the principal species responsible for cutaneous and visceral leishmaniases, respectively. Domestic dogs are the main reservoirs of visceral leishmaniasis, while rodents and marsupials are the main reservoirs for cutaneous leishmaniasis. It has also been suggested that dogs could play a role in transmission of cutaneous leishmaniasis. The identification of the species of Leishmania, the reservoirs, and the vectors involved in each particular transmission cycle is critical for the establishment of control activities. Belo Horizonte has emerged as an endemic region for leishmaniases, however, epidemiological studies assessing the contribution of wild reservoirs to transmission are scarce in the area. The aim of this study was to investigate Leishmania spp. infection in possible reservoirs of an urbanized area. A high rate of infection was found in small mammals (64.9%) and dogs (DG1 30.4% and DG2 48.6%). The presence of L. infantum and L. braziliensis was detected in small mammals and dogs, and mixed infections by both species were detected in rodents which, to the best of our knowledge, is the first description of this phenomenon in an urban area. Additionally, L. amazonensis was detected in the canine samples. The possible role of these animals as a source of infection of the vector of each species of Leishmania identified should not be overlooked and should be taken into account in future control activities. The results of mixed infection by L. braziliensis and L. infantum in cosmopolitan rodents as M. musculus and R. rattus, may have important implications in the context of the control of leishmaniasis in urban areas, especially when considering that these rodents live in close relationship with human dwellings, especially those in more precarious conditions.es_ES
dc.description.sponsorshipThe authors wish to thank the Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG), the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Capes), the Fundação Oswaldo Cruz (FIOCRUZ) and European Community (EC - LeishEpiNetSA Consortium) for financially supporting the study. We are also grateful to the Centro de Controle de Zoonoses da Prefeitura de Belo Horizonte for assistance and logistic support, and to Zoraida del Carmen Fernandez Grillo for assistance in revising the text in English.es_ES
dc.publisherBioMed Central (BMC) es_ES
dc.subject.meshLeishmania braziliensis es_ES
dc.subject.meshLeishmania infantum es_ES
dc.subject.meshAnimals es_ES
dc.subject.meshBrazil es_ES
dc.subject.meshCities es_ES
dc.subject.meshCoinfection es_ES
dc.subject.meshDisease Reservoirs es_ES
dc.subject.meshDog Diseases es_ES
dc.subject.meshDogs es_ES
dc.subject.meshLeishmaniasis, Cutaneous es_ES
dc.subject.meshMice es_ES
dc.subject.meshRats es_ES
dc.subject.meshRodent Diseases es_ES
dc.subject.meshRodentia es_ES
dc.titleMixed infection of Leishmania infantum and Leishmania braziliensis in rodents from endemic urban area of the New World.es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.contributor.funderEuropean Union
dc.identifier.journalBMC veterinary researches_ES
dc.rights.accessRightsopen accesses_ES

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Atribución 4.0 Internacional
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