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dc.contributor.authorMazagatos, Clara 
dc.contributor.authorGodoy, Pere
dc.contributor.authorMuñoz Almagro, Carmen
dc.contributor.authorLarrauri, Amparo 
dc.contributor.authorPozo Sanchez, Francisco 
dc.contributor.authorIVE in Pregnant Women Working Group
dc.contributor.authorDelgado-Sanz, Concepcion 
dc.contributor.authorOliva Dominguez, Jesus Angel 
dc.contributor.authorGherasim, Alin Manuel 
dc.contributor.authorGallego Berciano, Pilar 
dc.date.accessioned2021-01-08T08:11:29Z
dc.date.available2021-01-08T08:11:29Z
dc.date.issued2020-12-14
dc.identifier.citationVaccine. 2020 Dec 14;38(52):8405-8410.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/11580
dc.description.abstractIntroduction: Influenza vaccination is recommended to pregnant women in Spain to reduce the risk of influenza-related complications. Influenza related hospitalizations pose a significant disease burden in children every year. Although children below 6 months are too young to be vaccinated, they can receive protection against influenza through vaccination of their mothers during pregnancy. We estimated the effectiveness of maternal influenza vaccination to prevent influenza hospitalizations in infants under 6 months of age. Methods: This is a retrospective pilot study, using data from the Severe Hospitalized Confirmed Influenza Cases (SHCIC) surveillance system in seasons 2017/18 and 2018/19 in Spain. Maternal vaccination status during pregnancy was collected for cases in children 6 months and younger hospitalized with confirmed influenza infection. Influenza vaccine effectiveness was estimated using the screening method, by comparing the proportion of children with vaccinated mothers during pregnancy (proportion of cases vaccinated, PCV), with the vaccination coverage among pregnant women in Spain (proportion of population vaccinated, PPV). Results: For all the study period, the PCV was 17% and the PPV was 35%. Influenza vaccination in mothers during pregnancy prevented influenza confirmed hospitalizations in infants aged 6 months and younger with a 61% (95%CI: 27-79%) effectiveness. Conclusions: In line with evidence from other countries, influenza vaccination during pregnancy protects infants up to 6 months of age from influenza hospitalizations in Spain. These results support current recommendations of influenza vaccination in pregnant women, and more studies are needed in Spain to confirm the double protection of maternal vaccination in mothers and infants.es_ES
dc.language.isoenges_ES
dc.publisherElsevier es_ES
dc.type.hasVersionSMURes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectInfluenzaes_ES
dc.subjectVaccinees_ES
dc.subjectPregnancyes_ES
dc.subjectScreeninges_ES
dc.titleEffectiveness of influenza vaccination during pregnancy to prevent severe infection in children under 6 months of age, Spain, 2017-2019es_ES
dc.typejournal articlees_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.identifier.pubmedID32741669es_ES
dc.format.volume38es_ES
dc.format.number52es_ES
dc.format.page8405-8410es_ES
dc.identifier.doi10.1016/j.vaccine.2020.07.014es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1873-2518
dc.relation.publisherversionhttps://doi.org/10.1016/j.vaccine.2020.07.014es_ES
dc.identifier.journalVaccinees_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Attribution-NonCommercial-NoDerivatives 4.0 Internacional