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dc.contributor.authorFernández-Natal, I
dc.contributor.authorSaez-Nieto, Juan A 
dc.contributor.authorRodríguez-Lázaro, David
dc.contributor.authorValdezate, Sylvia 
dc.contributor.authorParras-Padilla, T
dc.contributor.authorMedina-Pascual, Maria Jose 
dc.contributor.authorRodríguez-Pollán, R H
dc.contributor.authorBlom, J
dc.contributor.authorTauch, A
dc.contributor.authorSoriano, F
dc.date.accessioned2020-12-03T08:37:19Z
dc.date.available2020-12-03T08:37:19Z
dc.date.issued2016-03
dc.identifier.citationNew Microbes New Infect . 2016 Jan 22;10:116-21.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/11492
dc.description.abstractDuring a 12-year period we isolated five Corynebacterium argentoratense strains identified by phenotypic methods, including the use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) and 16S rRNA gene sequencing. In addition, antimicrobial susceptibility was determined, and genome sequencing for the detection of antibiotic resistance genes was performed. The organisms were isolated from blood and throat cultures and could be identified by all methods used. All strains were resistant to cotrimoxazole, and resistance to β-lactams was partly present. Two strains were resistant to erythromycin and clindamycin. The draft genome sequences of theses isolates revealed the presence of the erm(X) resistance gene that is embedded in the genetic structure of the transposable element Tn5423. Although rarely reported as a human pathogen, C. argentoratense can be involved in bacteraemia and probably in other infections. Our results also show that horizontal transfer of genes responsible for antibiotic resistance is occurring in this species.es_ES
dc.description.sponsorshipWe thank A. Acedo from AC-Gen Reading Life, SL, Valladolid, Spain, for his technical support in the whole genome shotgun sequencing. Supported in part by the Gerencia Regional de Salud, Junta de Castilla y León, Spain (research project GRS 698/A/2011).es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAntimicrobial resistancees_ES
dc.subjectCorynebacterium argentoratensees_ES
dc.subjectMALDI-TOFes_ES
dc.subjectclinical infectionses_ES
dc.subjectwhole genome sequencinges_ES
dc.titlePhenotypic, molecular characterization, antimicrobial susceptibility and draft genome sequence of Corynebacterium argentoratense strains isolated from clinical samples.es_ES
dc.typeArtículoes_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.identifier.pubmedID26933505es_ES
dc.format.volume10es_ES
dc.format.page116-21es_ES
dc.identifier.doi10.1016/j.nmni.2016.01.007es_ES
dc.contributor.funderJunta de Castilla y León
dc.description.peerreviewedes_ES
dc.identifier.e-issn2052-2975
dc.relation.publisherversionhttps://doi.org/10.1016/j.nmni.2016.01.007es_ES
dc.identifier.journalNew microbes and new infectionses_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/GRS 698/A/2011es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
This item is licensed under a: Attribution-NonCommercial-NoDerivatives 4.0 Internacional