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dc.contributor.authorÁlvaro-Meca, Alejandro
dc.contributor.authorSánchez-Lopez, Ainhoa
dc.contributor.authorResino, Rosa
dc.contributor.authorTamayo, Eduardo
dc.contributor.authorResino, Salvador 
dc.date.accessioned2020-11-25T10:59:39Z
dc.date.available2020-11-25T10:59:39Z
dc.date.issued2020-08-27
dc.identifier.citationEnviron Res . 2020 Aug 27;191:110102.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/11426
dc.description.abstractPneumonia is a common cause of morbidity and sepsis worldwide, mainly in the elderly. We evaluated the impact of short-term exposure to environmental factors on hospital admissions for sepsis-related pneumonia in a nationwide study in Spain. We conducted a bidirectional case-crossover study in patients who had sepsis-related pneumonia in 2013. Data were obtained from the Minimum Basic Data Set (MBDS) and the State Meteorological Agency (AEMET) of Spain. Conditional logistic regressions were used to evaluate the association between environmental factors (temperature, relative humidity, NO2, SO2, O3, PM10, and CO) and hospital admissions with sepsis-related pneumonia. A total of 3,262,758 hospital admissions were recorded in the MBDS, of which, 253,467 were patients with sepsis. Among those, 67,443 had sepsis-related pneumonia and zip code information. We found inverse associations [adjusted odds ratio (aOR) values < 1] between short-term exposure to temperature and hospital admissions for sepsis-related pneumonia. Moreover, short-term exposure to higher levels of relative humidity, NO2, SO2, O3, PM10, and CO were directly associated (aOR values > 1) with a higher risk of hospital admissions for sepsis-related pneumonia. Overall, the impact of environmental factors was more prominent with increasing age, mainly among the elderly aged 65 or over. Short-term exposure to environmental factors (temperature, relative humidity, NO2, SO2, O3, CO, and PM10) was associated with a higher risk of hospital admissions for sepsis-related pneumonia. Our findings support the role of environmental factors in monitoring the risk of hospital admissions for sepsis-related pneumonia and can help plan and prepare public health resources.es_ES
dc.description.sponsorshipThis research has been supported by Instituto de Salud Carlos III [grant # PI15/01451 to ET], “Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon” [grant #773/A/13 to ET], and PFIZER [grant number CT25-ESP01-01 to SR]es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.relation.isversionofPostprintes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAgees_ES
dc.subjectEnvironmentes_ES
dc.subjectICD-9-CMes_ES
dc.subjectPneumoniaes_ES
dc.subjectSepsises_ES
dc.titleEnvironmental factors are associated with hospital admissions for sepsis-related pneumonia: A bidirectional case-crossover design.es_ES
dc.typeArtículoes_ES
dc.rights.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.identifier.pubmedID32861723es_ES
dc.format.volume191es_ES
dc.format.page110102es_ES
dc.identifier.doi10.1016/j.envres.2020.110102es_ES
dc.contributor.funderInstituto de Salud Carlos III - ISCIII
dc.contributor.funderJunta de Castilla y León
dc.description.peerreviewedes_ES
dc.identifier.e-issn1096-0953
dc.relation.publisherversionhttps://doi.org/10.1016/j.envres.2020.110102es_ES
dc.identifier.journalEnvironmental researches_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/PI15/01451es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/773/A/13es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/ES/CT25-ESP01-01es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/embargoedAccesses_ES


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
This item is licensed under a: Attribution-NonCommercial-NoDerivatives 4.0 Internacional