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dc.contributor.authorKorcinska, M R
dc.contributor.authorDalsgaard Bjerre, K
dc.contributor.authorDam Rasmussen, L
dc.contributor.authorTvenstrup Jensen, E
dc.contributor.authorFischer, T K
dc.contributor.authorBarrasa, Alicia 
dc.contributor.authorEthelberg, S
dc.date.accessioned2020-11-23T10:44:56Z
dc.date.available2020-11-23T10:44:56Z
dc.date.issued2020
dc.identifier.citationEpidemiol Infect. 2020 Feb 17;148:e52.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/11394
dc.description.abstractNorovirus (NoV) infections occur very frequently yet are rarely diagnosed. In Denmark, NoV infections are not under surveillance. We aimed to collect and describe existing laboratory-based NoV data. National NoV laboratory data were collected for 2011-2018, including information on patient identification number, age and sex, requesting physician, analysis date and result. We defined positive patient-episodes by using a 30-day time window and performed descriptive and time series analysis. Diagnostic methods used were assessed through a survey. We identified 15 809 patient-episodes (11%) out of 142 648 tested patients with an increasing trend, 9366 in 2011 vs. 32 260 in 2018. This corresponded with a gradual introduction of polymerase chain reaction analysis in laboratories. The highest positivity rate was in patients aged <5 years (15%) or >85 years (17%). There was a large difference in test performance over five Danish geographical regions and a marked seasonal variation with peaks from December to February. This is the first analysis of national NoV laboratory data in Denmark. A future laboratory-based surveillance system may benefit public health measures by describing trend, burden and severity of seasons and possibly pinpoint hospital outbreaks.es_ES
dc.language.isoenges_ES
dc.publisherCambridge University Press es_ES
dc.type.hasVersionVoRes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectEpidemiologyes_ES
dc.subjectNorwalk agent and related viruseses_ES
dc.subjectHospital-acquired (nosocomial) infectionses_ES
dc.subjectNoroviruses_ES
dc.subjectSurveillancees_ES
dc.subject.meshCaliciviridae Infections es_ES
dc.subject.meshDisease Outbreaks es_ES
dc.subject.meshAdolescent es_ES
dc.subject.meshAdult es_ES
dc.subject.meshAged es_ES
dc.subject.meshAged, 80 and over es_ES
dc.subject.meshChild es_ES
dc.subject.meshChild, Preschool es_ES
dc.subject.meshDenmark es_ES
dc.subject.meshFemale es_ES
dc.subject.meshHumans es_ES
dc.subject.meshInfant es_ES
dc.subject.meshInfant, Newborn es_ES
dc.subject.meshMale es_ES
dc.subject.meshMiddle Aged es_ES
dc.subject.meshSeasons es_ES
dc.subject.meshYoung Adult es_ES
dc.titleDetection of norovirus infections in Denmark, 2011-2018.es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.pubmedID32063241es_ES
dc.format.volume148es_ES
dc.format.pagee52es_ES
dc.identifier.doi10.1017/S0950268820000461es_ES
dc.description.peerreviewedes_ES
dc.identifier.e-issn1469-4409
dc.relation.publisherversionhttps://doi.org/10.1017/S0950268820000461es_ES
dc.identifier.journalEpidemiology and infectiones_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsopen accesses_ES


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Atribución 4.0 Internacional
Este Item está sujeto a una licencia Creative Commons: Atribución 4.0 Internacional