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dc.contributor.authorLucas Dato, Ana
dc.contributor.authorPacheco-Tenza, María Isabel
dc.contributor.authorBorrajo Brunete, Emilio
dc.contributor.authorMartínez López, Belén
dc.contributor.authorGarcía López, María
dc.contributor.authorGonzález Cuello, Inmaculada
dc.contributor.authorGregori Colomé, Joan
dc.contributor.authorNavarro Cots, María
dc.contributor.authorSaugar, Jose Maria 
dc.contributor.authorGarcía-Vazquez, Elisa
dc.contributor.authorRuiz-Maciá, José Antonio
dc.contributor.authorLlenas-García, Jara
dc.identifier.citationPathogens. 2020 Aug; 9(8): 601.es_ES
dc.description.abstractStrongyloidiasis is a parasitic disease with global prevalence. In Spain, autochthonous cases are concentrated in the Mediterranean basin. We aimed to analyze clinical and epidemiological characteristics of Strongyloides stercoralis infection in Vega Baja del Segura (Spain), comparing autochthonous versus imported cases. Observational retrospective study of all strongyloidiasis cases from January 2009 to January 2019. Cases were diagnosed by stool larvae visualization, positive culture, PCR, Strongyloides serology, and/or compatible histology. We included 36 patients (21 men) with a mean age of 60.8 years ±17.6; 15 cases were autochthonous and 21 imported 80.9% from Latin America. Autochthonous cases were associated with older age (mean 71.3 vs. 53.3 years; p = 0.002), male sex (odds ratio (OR) 5.33; 95% confidence interval (CI) 1.15-24.68; p = 0.041), and agricultural activity (OR 13.5; 95% CI 2.4-73.7; p = 0.002). Fourteen were asymptomatic, three autochthonous cases presented with hyperinfection syndrome, and two patients died. There was no difference between autochthonous versus imported origin in eosinophilia at diagnosis (93.3% vs. 75%; p = 0.207), treatment received, or clinical response (85.7% vs. 88.9% cured; p = 1). In our region, imported strongyloidiasis coexists with autochthonous cases, which are mainly in older male farmers who are diagnosed at more advanced stages. Systematic screening programs are needed.es_ES
dc.description.sponsorshipThis study has been funded by the Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FISABIO) in the 3rd Call for Aid for the Development of Research Projects for Emerging Groups (Mode B) (UGP-19-031) including funds to cover publication costs.es_ES
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI) es_ES
dc.subject.meshStrongyloides stercoralises_ES
dc.subject.meshEosinophilia es_ES
dc.subject.meshImmunosuppression es_ES
dc.subject.meshIvermectin es_ES
dc.subject.meshStrongyloidiasis es_ES
dc.titleStrongyloidiasis in Southern Alicante (Spain): Comparative Retrospective Study of Autochthonous and Imported Cases.es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución 4.0 Internacional*
dc.identifier.journalPathogens (Basel, Switzerland)es_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.rights.accessRightsopen accesses_ES

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