Show simple item record

dc.contributor.authorRodríguez, Javier M
dc.contributor.authorLuque, Daniel 
dc.date.accessioned2020-06-11T09:38:56Z
dc.date.available2020-06-11T09:38:56Z
dc.date.issued2019
dc.identifier.citationAdv Exp Med Biol . 2019;1215:45-68.es_ES
dc.identifier.issn0065-2598es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/10344
dc.description.abstractTo initiate infection, non-enveloped viruses must recognize a target cell and penetrate the cell membrane by pore formation or membrane lysis. Rotaviruses are non-enveloped dsRNA viruses that infect the mature intestinal epithelium. They are major etiologic agents of diarrheal disease in human infants, as well as in young individuals of various avian and mammalian species. Rotavirus entry into the cell is a complex multistep process initiated by the interaction of the tip of the viral spike with glycan ligands at the cell surface, and driven by conformational changes of the proteins present in the outer protein capsid, the viral machinery for entry. This review feeds on the abundant structural information produced for rotavirus during the past 30 years and focuses on the structure and the dynamics of the rotavirus entry machinery. We survey the current models for rotavirus entry into cells.es_ES
dc.language.isoenges_ES
dc.publisherSpringer Verlages_ES
dc.relation.isversionofPostprintes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshRotavirus es_ES
dc.subject.meshRotavirus Infections es_ES
dc.subject.meshVirus Internalization es_ES
dc.subject.meshAnimals es_ES
dc.subject.meshCell Membrane es_ES
dc.subject.meshHumans es_ES
dc.subject.meshModels, Biologicales_ES
dc.titleStructural Insights into Rotavirus Entry.es_ES
dc.typeArtículoes_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.identifier.pubmedID31317495es_ES
dc.format.volume1215es_ES
dc.format.page45-68es_ES
dc.identifier.doi10.1007/978-3-030-14741-9_3es_ES
dc.description.peerreviewedes_ES
dc.relation.publisherversionhttps://doi.org/10.1007/978-3-030-14741-9_3es_ES
dc.identifier.journalAdvances in experimental medicine and biologyes_ES
dc.repisalud.centroISCIII::Centro Nacional de Microbiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


Files in this item

Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail
Acceso Abierto
Thumbnail

This item appears in the following Collection(s)

Show simple item record

Atribución-NoComercial-CompartirIgual 4.0 Internacional
This item is licensed under a: Atribución-NoComercial-CompartirIgual 4.0 Internacional