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dc.contributor.authorGarcía-Esquinas, Esther 
dc.contributor.authorJiménez, Angélica
dc.contributor.authorPastor-Barriuso, Roberto 
dc.contributor.authorJones, Miranda R
dc.contributor.authorPerez-Gomez, Beatriz 
dc.contributor.authorNavas-Acien, Ana
dc.contributor.authorTellez-Plaza, Maria 
dc.date.accessioned2020-06-01T07:45:13Z
dc.date.available2020-06-01T07:45:13Z
dc.date.issued2018
dc.identifier.citationEnviron Int . 2018 Aug;117:260-267.es_ES
dc.identifier.urihttp://hdl.handle.net/20.500.12105/10233
dc.description.abstractThe major decrease in exposure to secondhand smoke (SHS) in public places in recent decades could have contributed to the decline in smoking-related cancer mortality observed in the US population. Prospective study among 11,856 non-smoking adults aged ≥40 years who participated in NHANES 1988-1994 or 1999-2004 and were followed for mortality through 2006. We estimated the amount of change in cancer mortality over time attributed to the intermediate pathway of changes in SHS exposure in public places, after adjustment for risk factors and SHS exposure at home. The adjusted smoking-related cancer mortality rate ratios (95% CI) for a two-fold increase in serum cotinine and a 1-hour increase in occupational SHS exposure time were 1.10 (1.03, 1.17) and 1.14 (1.06, 1.24) for all-cancer, and 1.13 (1.03, 1.24) and 1.14 (1.02, 1.26) for smoking-related cancer, respectively. The absolute reduction in mortality comparing 1999-2004 to 1988-1994 was 75.8 (-25.5, 177.0) and 77.0 (2.6, 151.4) deaths/100,000 person-years, for all-cancer and smoking-related cancer, respectively. Among these avoided all-cancer deaths, 45.8 (2.8, 89.5) and 18.1 (-1.2, 39.6)/100,000 person-year were attributable to changes in serum cotinine concentrations and occupational SHS exposure time, respectively. The corresponding numbers of smoking-related cancer avoided deaths were 36.4 (0.7, 72.8) and 9.9 (-3.8, 24.9)/100,000 person-year. Declines in SHS exposure were associated with reductions in all-cancer and smoking-related cancer mortality, supporting that smoking bans in public places may have reduced cancer mortality among non-smoking adults.es_ES
dc.description.sponsorshipThis work was supported by the Strategic Action for Research in Health sciences (CP12/03080; PI15/00071); CIBERESP and CIBEROBN. The Strategic Action for Research in Health Sciences, CIBEROBN and CIBERESP are initiatives from the Carlos the third National Health Institutes in Madrid and the Spanish Ministry of Economy and Competitiveness and are co-funded with European Funds for Regional Development (FEDER).es_ES
dc.language.isoenges_ES
dc.publisherElsevier es_ES
dc.type.hasVersionSMURes_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshAdult es_ES
dc.subject.meshHumans es_ES
dc.subject.meshLung Neoplasms es_ES
dc.subject.meshProspective Studies es_ES
dc.subject.meshSmoking es_ES
dc.subject.meshTobacco Smoke Pollution es_ES
dc.titleImpact of declining exposure to secondhand tobacco smoke in public places to decreasing smoking-related cancer mortality in the US population.es_ES
dc.typejournal articlees_ES
dc.rights.licenseAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.identifier.pubmedID29775915es_ES
dc.format.volume117es_ES
dc.format.page260-267es_ES
dc.identifier.doi10.1016/j.envint.2018.05.008es_ES
dc.contributor.funderInstituto de Salud Carlos III 
dc.contributor.funderMinisterio de Economía y Competitividad (España) 
dc.contributor.funderUnión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF) 
dc.description.peerreviewedes_ES
dc.identifier.e-issn1873-6750es_ES
dc.relation.publisherversionhttps://doi.org/10.1016/j.envint.2018.05.008es_ES
dc.identifier.journalEnvironment internationales_ES
dc.repisalud.centroISCIII::Centro Nacional de Epidemiologíaes_ES
dc.repisalud.institucionISCIIIes_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/CP12/03080es_ES
dc.relation.projectIDinfo:eu_repo/grantAgreement/ES/PI15/00071es_ES
dc.rights.accessRightsopen accesses_ES


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Atribución-NoComercial-CompartirIgual 4.0 Internacional
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