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A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens.
CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells
Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence
Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells.
Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells
Polμ deficiency increases resistance to oxidative damage and delays liver aging
The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites